Cargando…

A Multicenter, Randomized, Double-blind, Parallel, Placebo-controlled Clinical Study to Evaluate the Efficacy and Safety of a Nicotine Mint Lozenge (2 and 4 mg) in Smoking Cessation

OBJECTIVE: To evaluate the efficacy in smoking cessation and safety of 2 and 4 mg nicotine mint lozenges in Chinese adult smokers. METHODS: This was a multicenter, randomized, stratified, double-blind, placebo-controlled, parallel-group study. The low-dependence stratum included 483 smokers (241 ran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Dan, Kotler, Mitchell, Kang, Jian, Wang, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012347/ https://www.ncbi.nlm.nih.gov/pubmed/31658113 http://dx.doi.org/10.1097/ADM.0000000000000547

Ejemplares similares

Pharmacokinetic characterization of three novel 4-mg nicotine lozenges
por: Sukhija, Manpreet, et al.
Publicado: (2018)

Smoking cessation or reduction with nicotine replacement therapy: a placebo-controlled double blind trial with nicotine gum and inhaler
por: Kralikova, Eva, et al.
Publicado: (2009)

The efficacy and safety of varenicline alone versus in combination with nicotine lozenges for smoking cessation among hospitalised smokers (VANISH): study protocol for a randomised, placebo-controlled trial
por: Gobarani, Rukshar Kaizerali, et al.
Publicado: (2020)

Randomized Trial to Compare Smoking Cessation Rates of Snus, With and Without Smokeless Tobacco Health-Related Information, and a Nicotine Lozenge
por: Nelson, Paul R, et al.
Publicado: (2019)

Pharmacokinetics, safety and efficacy from randomized controlled trials of 1 and 2 mg nicotine bitartrate lozenges (Nicotinell(®))
por: Dautzenberg, Bertrand, et al.
Publicado: (2007)

Efficacy of a nicotine mouth spray in smoking cessation: a randomised, double-blind trial
por: Tønnesen, Philip, et al.
Publicado: (2012)

Efficacy of 8 mg lidocaine and 2 mg cetylpyridinium chloride (CPC) fixed-combination lozenges on sore throat pain intensity compared with 1 mg lidocaine and 2 mg CPC fixed-combination lozenges in subjects with sore throat due to upper respiratory tract infection: a randomized double-blind parallel-group single-dose study
por: Donath, Frank, et al.
Publicado: (2018)

Randomized, placebo-controlled, double-blind trial of Swedish snus for smoking reduction and cessation
por: Joksić, Gordana, et al.
Publicado: (2011)

Sociodemographic and Smoking Behavioral Predictors Associated with Smoking Cessation According to Follow-up Periods: A Randomized, Double-blind, Placebo-controlled Trial of Transdermal Nicotine Patches
por: Myung, Seung Kwon, et al.
Publicado: (2007)

Effect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial
por: Lengsfeld, Sophia, et al.
Publicado: (2023)

Single‐Dose Bioequivalence of Two Mini Nicotine Lozenge Formulations
por: Rasmussen, Scott C., et al.
Publicado: (2017)

Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial
por: Caponnetto, Pasquale, et al.
Publicado: (2023)

Protocol for the Smoking, Nicotine and Pregnancy (SNAP) trial: double-blind, placebo-randomised, controlled trial of nicotine replacement therapy in pregnancy
por: Coleman, Tim, et al.
Publicado: (2007)

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Ambroxol Hard-Boiled Lozenges in Patients with Acute Pharyngitis
por: Sousa, Rita, et al.
Publicado: (2019)

Lack of effects of simvastatin on smoking cessation in humans: A double-blind, randomized, placebo-controlled clinical study
por: Ingrand, Isabelle, et al.
Publicado: (2018)

The efficacy and safety of a nicotine conjugate vaccine (NicVAX(®)) or placebo co-administered with varenicline (Champix(®)) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial
por: Hoogsteder, Philippe HJ, et al.
Publicado: (2012)

Methods for smoking cessation and treatment of nicotine dependence
por: Silveira Balbani, Aracy Pereira, et al.
Publicado: (2015)

Nicotine receptor partial agonists for smoking cessation
por: Livingstone-Banks, Jonathan, et al.
Publicado: (2023)

Nicotine receptor partial agonists for smoking cessation
por: Livingstone-Banks, Jonathan, et al.
Publicado: (2023)

Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi‐centre, randomised, placebo‐controlled, double‐blind, parallel‐group trial (DoriPha)
por: Palm, Jürgen, et al.
Publicado: (2018)

A multicentre, randomised, double-blind, single-dose study assessing the efficacy of AMC/DCBA Warm lozenge or AMC/DCBA Cool lozenge in the relief of acute sore throat
por: Wade, Alan G, et al.
Publicado: (2011)

Phosphate of Lime Lozenges
Publicado: (1858)

Nicotine Free Herbal Composition for Smoking De-Addiction - A Placebo Controlled, Double Blind, Randomized, Multicentric Clinical Study
por: Tamoli, Sanjay Motilal, et al.
Publicado: (2023)

Multi-Sensor Approach for the Monitoring of Halitosis Treatment via Lactobacillus brevis (CD2)—Containing Lozenges—A Randomized, Double-Blind Placebo-Controlled Clinical Trial
por: Marchetti, Enrico, et al.
Publicado: (2015)

Immunogenicity and Smoking Cessation Outcomes for a Novel Nicotine Immunotherapeutic
por: Hatsukami, Dorothy K., et al.
Publicado: (2011)

Nicotine Vaccines to Assist with Smoking Cessation: Current Status of Research
por: Raupach, Tobias, et al.
Publicado: (2012)

Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation
por: Mohamed, Tasnim S., et al.
Publicado: (2015)

Are electronic nicotine delivery systems an effective smoking cessation tool?
por: Lam, Christine, et al.
Publicado: (2015)

Effects of Genetic Variants in the Nicotine Metabolism Pathway on Smoking Cessation
por: Li, Huijie, et al.
Publicado: (2022)

Nationwide experiences with youth-targeted smoking and nicotine product cessation
por: Rasmussen, Sofie Kirstine Bergman, et al.
Publicado: (2023)

Service's Milk Salt Lozenges
Publicado: (1886)

The Role of Lozenge in Drosophila Hematopoiesis
por: Koranteng, Ferdinand, et al.
Publicado: (2020)

The effect of N-acetylcysteine on brain glutamate and gamma-aminobutyric acid concentrations and on smoking cessation: A randomized, double-blind, placebo-controlled trial
por: Schulte, MHJ, et al.
Publicado: (2017)

Efficacy and Safety of Cytisine in Combination with a Community Pharmacists’ Counselling for Smoking Cessation in Thailand: A Randomized Double-Blinded Placebo-Controlled Trial
por: Phusahat, Pum, et al.
Publicado: (2022)

MintDuino
por: Kelly, James
Publicado: (2011)

Randomized, double-masked, placebo-controlled clinical study of the effectiveness of zinc acetate lozenges on common cold symptoms in allergy-tested subjects
por: Petrus, Edward J., et al.
Publicado: (1998)

Carotid artery plaque intervention with Tongxinluo capsule (CAPITAL): A multicenter randomized double-blind parallel-group placebo-controlled study
por: Zhang, Mei, et al.
Publicado: (2019)

Use of a liquid nicotine delivery product to promote smoking cessation
por: Geimer, Nicholas, et al.
Publicado: (2010)

Nicotine dependence and psychological distress: outcomes and clinical implications in smoking cessation
por: Cosci, Fiammetta, et al.
Publicado: (2011)

Varenicline for Smoking Cessation: Nausea Severity and Variation in Nicotinic Receptor Genes
por: Swan, Gary E., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_r495scs3vlgmkjo4v6igqors08