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Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative

The reproducibility crisis triggered worldwide initiatives to improve rigor, reproducibility, and transparency in biomedical research. There are many examples of scientists, journals, and funding agencies adopting responsible research practices. The QUEST (Quality-Ethics-Open Science-Translation) Ce...

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Detalles Bibliográficos
Autores principales: Strech, Daniel, Weissgerber, Tracey, Dirnagl, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012388/
https://www.ncbi.nlm.nih.gov/pubmed/32045410
http://dx.doi.org/10.1371/journal.pbio.3000576
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author Strech, Daniel
Weissgerber, Tracey
Dirnagl, Ulrich
author_facet Strech, Daniel
Weissgerber, Tracey
Dirnagl, Ulrich
author_sort Strech, Daniel
collection PubMed
description The reproducibility crisis triggered worldwide initiatives to improve rigor, reproducibility, and transparency in biomedical research. There are many examples of scientists, journals, and funding agencies adopting responsible research practices. The QUEST (Quality-Ethics-Open Science-Translation) Center offers a unique opportunity to examine the role of institutions. The Berlin Institute of Health founded QUEST to increase the likelihood that research conducted at this large academic medical center would be trustworthy, useful for scientists and society, and ethical. QUEST researchers perform “science of science” studies to understand problems with standard practices and develop targeted solutions. The staff work with institutional leadership and local scientists to incentivize and support responsible practices in research, funding, and hiring. Some activities described in this paper focus on the institution, whereas others may benefit the national and international scientific community. Our experience, approaches, and recommendations will be informative for faculty leadership, administrators, and researchers interested in improving scientific practice.
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spelling pubmed-70123882020-02-21 Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative Strech, Daniel Weissgerber, Tracey Dirnagl, Ulrich PLoS Biol Community Page The reproducibility crisis triggered worldwide initiatives to improve rigor, reproducibility, and transparency in biomedical research. There are many examples of scientists, journals, and funding agencies adopting responsible research practices. The QUEST (Quality-Ethics-Open Science-Translation) Center offers a unique opportunity to examine the role of institutions. The Berlin Institute of Health founded QUEST to increase the likelihood that research conducted at this large academic medical center would be trustworthy, useful for scientists and society, and ethical. QUEST researchers perform “science of science” studies to understand problems with standard practices and develop targeted solutions. The staff work with institutional leadership and local scientists to incentivize and support responsible practices in research, funding, and hiring. Some activities described in this paper focus on the institution, whereas others may benefit the national and international scientific community. Our experience, approaches, and recommendations will be informative for faculty leadership, administrators, and researchers interested in improving scientific practice. Public Library of Science 2020-02-11 /pmc/articles/PMC7012388/ /pubmed/32045410 http://dx.doi.org/10.1371/journal.pbio.3000576 Text en © 2020 Strech et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Community Page
Strech, Daniel
Weissgerber, Tracey
Dirnagl, Ulrich
Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative
title Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative
title_full Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative
title_fullStr Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative
title_full_unstemmed Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative
title_short Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative
title_sort improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative
topic Community Page
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012388/
https://www.ncbi.nlm.nih.gov/pubmed/32045410
http://dx.doi.org/10.1371/journal.pbio.3000576
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