Characterisation of the in vitro activity of a Nitazoxanide-N-methyl-1H-benzimidazole hybrid molecule against albendazole and nitazoxanide susceptible and resistant strains of Giardia intestinalis and its in vivo giardicidal activity

BACKGROUND: It was previously demonstrated that CMC-20, a nitazoxanide and N-methyl-1H-benzimidazole hybrid molecule, had higher in vitro activity against Giardia intestinalis WB strain than metronidazole and albendazole and similar to nitazoxanide. OBJETIVES: To evaluate the in vitro activity of CM...

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Detalles Bibliográficos
Autores principales: Matadamas-Martínez, Félix, Nogueda-Torres, Benjamín, Castillo, Rafael, Hernández-Campos, Alicia, Barrera-Valdes, María de la Luz, León-Ávila, Gloria, Hernández, José Manuel, Yépez-Mulia, Lilián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012584/
https://www.ncbi.nlm.nih.gov/pubmed/32049098
http://dx.doi.org/10.1590/0074-02760190348

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