A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice

Amyloids are a class of protein with unique self-aggregation properties, and their aberrant accumulation can lead to cellular dysfunctions associated with neurodegenerative diseases. While genetic and environmental factors can influence amyloid formation, molecular triggers and/or facilitators are n...

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Detalles Bibliográficos
Autores principales: Sampson, Timothy R, Challis, Collin, Jain, Neha, Moiseyenko, Anastasiya, Ladinsky, Mark S, Shastri, Gauri G, Thron, Taren, Needham, Brittany D, Horvath, Istvan, Debelius, Justine W, Janssen, Stefan, Knight, Rob, Wittung-Stafshede, Pernilla, Gradinaru, Viviana, Chapman, Matthew, Mazmanian, Sarkis K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012599/
https://www.ncbi.nlm.nih.gov/pubmed/32043464
http://dx.doi.org/10.7554/eLife.53111

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