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Notochord vacuoles absorb compressive bone growth during zebrafish spine formation
The vertebral column or spine assembles around the notochord rod which contains a core made of large vacuolated cells. Each vacuolated cell possesses a single fluid-filled vacuole, and loss or fragmentation of these vacuoles in zebrafish leads to spine kinking. Here, we identified a mutation in the ki...
Autores principales: | Bagwell, Jennifer, Norman, James, Ellis, Kathryn, Peskin, Brianna, Hwang, James, Ge, Xiaoyan, Nguyen, Stacy V, McMenamin, Sarah K, Stainier, Didier YR, Bagnat, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012607/ https://www.ncbi.nlm.nih.gov/pubmed/31995030 http://dx.doi.org/10.7554/eLife.51221 |
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