RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates

Increasing Neisseria gonorrhoeae resistance to ceftriaxone, the last antibiotic recommended for empiric gonorrhea treatment, poses an urgent public health threat. However, the genetic basis of reduced susceptibility to ceftriaxone is not completely understood: while most ceftriaxone resistance in cl...

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Detalles Bibliográficos
Autores principales: Palace, Samantha G, Wang, Yi, Rubin, Daniel HF, Welsh, Michael A, Mortimer, Tatum D, Cole, Kevin, Eyre, David W, Walker, Suzanne, Grad, Yonatan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012608/
https://www.ncbi.nlm.nih.gov/pubmed/32011233
http://dx.doi.org/10.7554/eLife.51407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012608/
https://www.ncbi.nlm.nih.gov/pubmed/32011233
http://dx.doi.org/10.7554/eLife.51407

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