Cargando…

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair

DNA double strand breaks (DSBs) have detrimental effects on cell survival and genomic stability, and are related to cancer and other human diseases. In this study, we identified microtubule-depolymerizing kinesin Kif2C as a protein associated with DSB-mimicking DNA templates and known DSB repair pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Songli, Paydar, Mohammadjavad, Wang, Feifei, Li, Yanqiu, Wang, Ling, Barrette, Benoit, Bessho, Tadayoshi, Kwok, Benjamin H, Peng, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012618/
https://www.ncbi.nlm.nih.gov/pubmed/31951198
http://dx.doi.org/10.7554/eLife.53402