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Contribution of TGF-Beta-Mediated NLRP3-HMGB1 Activation to Tubulointerstitial Fibrosis in Rat With Angiotensin II-Induced Chronic Kidney Disease

Fibrosis is a common phenotype that often leads to the progression of blood pressure-induced chronic kidney disease (CKD). TGF-beta plays an important role in promoting pathogenesis, and NLRP3 is a critical mediator in the progression of blood pressure-induced CKD. However, the pathophysiological ro...

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Detalles Bibliográficos
Autores principales:	Zhang, Kaimin, Fan, Chun, Cai, Dongpeng, Zhang, Yi, Zuo, Rui, Zhu, Li, Cao, Yue, Zhang, Jian, Liu, Chao, Chen, Yang, Liang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012792/ https://www.ncbi.nlm.nih.gov/pubmed/32117956 http://dx.doi.org/10.3389/fcell.2020.00001

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