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Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma

The ability to return to work after treatment of diseases is an important issue. Aim of this study is to compare surgery and conservative management focusing on clinical outcome and ability to return to work in patients with intramedullary spinal cord ependymoma. Retrospective, single center study....

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Autores principales: Behmanesh, Bedjan, Gessler, Florian, Won, Sae-Yeon, Dubinski, Daniel, Quick-Weller, Johanna, Imoehl, Lioba, Seifert, Volker, Marquardt, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012826/
https://www.ncbi.nlm.nih.gov/pubmed/32047239
http://dx.doi.org/10.1038/s41598-020-59328-1
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author Behmanesh, Bedjan
Gessler, Florian
Won, Sae-Yeon
Dubinski, Daniel
Quick-Weller, Johanna
Imoehl, Lioba
Seifert, Volker
Marquardt, Gerhard
author_facet Behmanesh, Bedjan
Gessler, Florian
Won, Sae-Yeon
Dubinski, Daniel
Quick-Weller, Johanna
Imoehl, Lioba
Seifert, Volker
Marquardt, Gerhard
author_sort Behmanesh, Bedjan
collection PubMed
description The ability to return to work after treatment of diseases is an important issue. Aim of this study is to compare surgery and conservative management focusing on clinical outcome and ability to return to work in patients with intramedullary spinal cord ependymoma. Retrospective, single center study. The neurological status at first presentation, as well as in long-term follow-up, were assessed using the modified McCormick Disability Scale and modified Rankin Scale. The study population consisted of 56 patients, 23 (41%) were managed conservatively and 33 (59%) underwent microsurgical resection. The median age was 47.5 years in the conservative group and 44.5 in the surgical group. At first admission 18 of conservatively treated and 28 of surgically treated patients were employed, p = 0.7. At the last follow-up 15 (83%) of conservatively and 10 (36%) of surgically treated patients returned to work, p = 0.002. The median modified McCormick score in both groups (conservative vs. surgical) was at admission 1 vs. 1, p = 1.0 and at last follow up 1 vs. 2.5, p = 0.001. Patients clinical outcome in the surgical group was significantly reduced at last follow up as assessed by the modified Rankin Scale (mRs score of 0–2) at admission 100% vs. 100% and last follow-up 94% vs. 57%, p = 0.007. In our investigated study population, conservatively managed patients revealed a significantly better outcome and were more often able to return to work.
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spelling pubmed-70128262020-02-21 Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma Behmanesh, Bedjan Gessler, Florian Won, Sae-Yeon Dubinski, Daniel Quick-Weller, Johanna Imoehl, Lioba Seifert, Volker Marquardt, Gerhard Sci Rep Article The ability to return to work after treatment of diseases is an important issue. Aim of this study is to compare surgery and conservative management focusing on clinical outcome and ability to return to work in patients with intramedullary spinal cord ependymoma. Retrospective, single center study. The neurological status at first presentation, as well as in long-term follow-up, were assessed using the modified McCormick Disability Scale and modified Rankin Scale. The study population consisted of 56 patients, 23 (41%) were managed conservatively and 33 (59%) underwent microsurgical resection. The median age was 47.5 years in the conservative group and 44.5 in the surgical group. At first admission 18 of conservatively treated and 28 of surgically treated patients were employed, p = 0.7. At the last follow-up 15 (83%) of conservatively and 10 (36%) of surgically treated patients returned to work, p = 0.002. The median modified McCormick score in both groups (conservative vs. surgical) was at admission 1 vs. 1, p = 1.0 and at last follow up 1 vs. 2.5, p = 0.001. Patients clinical outcome in the surgical group was significantly reduced at last follow up as assessed by the modified Rankin Scale (mRs score of 0–2) at admission 100% vs. 100% and last follow-up 94% vs. 57%, p = 0.007. In our investigated study population, conservatively managed patients revealed a significantly better outcome and were more often able to return to work. Nature Publishing Group UK 2020-02-11 /pmc/articles/PMC7012826/ /pubmed/32047239 http://dx.doi.org/10.1038/s41598-020-59328-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Behmanesh, Bedjan
Gessler, Florian
Won, Sae-Yeon
Dubinski, Daniel
Quick-Weller, Johanna
Imoehl, Lioba
Seifert, Volker
Marquardt, Gerhard
Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma
title Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma
title_full Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma
title_fullStr Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma
title_full_unstemmed Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma
title_short Return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma
title_sort return to work and clinical outcome after surgical treatment and conservative management of patients with intramedullary spinal cord ependymoma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012826/
https://www.ncbi.nlm.nih.gov/pubmed/32047239
http://dx.doi.org/10.1038/s41598-020-59328-1
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