Androgen receptor-binding sites are highly mutated in prostate cancer

Androgen receptor (AR) signalling is essential in nearly all prostate cancers. Any alterations to AR-mediated transcription can have a profound effect on carcinogenesis and tumor growth. While mutations of the AR protein have been extensively studied, little is known about those somatic mutations th...

Descripción completa

Detalles Bibliográficos
Autores principales: Morova, Tunç, McNeill, Daniel R., Lallous, Nada, Gönen, Mehmet, Dalal, Kush, Wilson, David M., Gürsoy, Attila, Keskin, Özlem, Lack, Nathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012874/
https://www.ncbi.nlm.nih.gov/pubmed/32047165
http://dx.doi.org/10.1038/s41467-020-14644-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012874/
https://www.ncbi.nlm.nih.gov/pubmed/32047165
http://dx.doi.org/10.1038/s41467-020-14644-y

Ejemplares similares