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Bacterial DNA promotes Tau aggregation

A hallmark feature of Alzheimer’s disease (AD) and other tauopathies is the misfolding, aggregation and cerebral accumulation of tau deposits. Compelling evidence indicates that misfolded tau aggregates are neurotoxic, producing synaptic loss and neuronal damage. Misfolded tau aggregates are able to...

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Detalles Bibliográficos
Autores principales: Tetz, George, Pinho, Michelle, Pritzkow, Sandra, Mendez, Nicolas, Soto, Claudio, Tetz, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012890/
https://www.ncbi.nlm.nih.gov/pubmed/32047247
http://dx.doi.org/10.1038/s41598-020-59364-x