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Major Histocompatibility Complex Binding, Eluted Ligands, and Immunogenicity: Benchmark Testing and Predictions

Antidrug antibody (ADA) responses impact drug safety, potency, and efficacy. It is generally assumed that ADA responses are associated with human leukocyte antigen (HLA) class II-restricted CD4+ T-cell reactivity. Although this review does not address ADA responses per se, the analysis presented her...

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Detalles Bibliográficos
Autores principales:	Paul, Sinu, Grifoni, Alba, Peters, Bjoern, Sette, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012937/ https://www.ncbi.nlm.nih.gov/pubmed/32117208 http://dx.doi.org/10.3389/fimmu.2019.03151

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