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Pristine and Hydroxylated Fullerenes Prevent the Aggregation of Human Islet Amyloid Polypeptide and Display Different Inhibitory Mechanisms

Protein aggregation, involving the formation of dimers, oligomers, and fibrils, is associated with many human diseases. Type 2 diabetes is one of the common amyloidosis and linked with the aggregation of human islet amyloid polypeptide (hIAPP). A series of nanoparticles are reported to be able to in...

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Detalles Bibliográficos
Autores principales:	Bai, Cuiqin, Lao, Zenghui, Chen, Yujie, Tang, Yiming, Wei, Guanghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013002/ https://www.ncbi.nlm.nih.gov/pubmed/32117877 http://dx.doi.org/10.3389/fchem.2020.00051

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