Combined treatment with N‐acetylcysteine and gefitinib overcomes drug resistance to gefitinib in NSCLC cell line

We aimed to explore the molecular substrate underlying EGFR‐TKI resistance and investigate the effects of N‐acetylcysteine (NAC) on reversing EGFR‐TKI resistance. In the current research, the effects of NAC in combination with gefitinib on reversing gefitinib resistance were examined using CCK‐8 ass...

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Detalles Bibliográficos
Autores principales: Li, Jun, Wang, Xiao‐Hui, Hu, Jing, Shi, Meng, Zhang, Lu, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013061/
https://www.ncbi.nlm.nih.gov/pubmed/31891230
http://dx.doi.org/10.1002/cam4.2610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013061/
https://www.ncbi.nlm.nih.gov/pubmed/31891230
http://dx.doi.org/10.1002/cam4.2610

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