Epistatic effect of TLR3 and cGAS‐STING‐IKKε‐TBK1‐IFN signaling variants on colorectal cancer risk

OBJECTIVE: The TLR3/cGAS‐STING‐IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in these genes on the risk of sporadic colorectal cancer (CR...

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Detalles Bibliográficos
Autores principales: Catalano, Calogerina, da Silva Filho, Miguel Inacio, Frank, Christoph, Lu, Shun, Jiraskova, Katerina, Vymetalkova, Veronika, Levy, Miroslav, Liska, Vaclav, Vycital, Ondrej, Naccarati, Alessio, Vodickova, Ludmila, Hemminki, Kari, Vodicka, Pavel, Weber, Alexander N. R., Försti, Asta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013077/
https://www.ncbi.nlm.nih.gov/pubmed/31869529
http://dx.doi.org/10.1002/cam4.2804

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