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Post-treatment with Posiphen Reduces Endoplasmic Reticulum Stress and Neurodegeneration in Stroke Brain
Acetylcholinesterase (AChE) inhibitors have protective and anti-inflammatory actions against brain injury, mediated by nicotinic α7 cholinergic receptor activation. The use of AChE inhibitors in patients is limited by systemic cholinergic side effects. Posiphen, a stereoisomer of the AChE inhibitor...
Autores principales: | Yu, Seong-Jin, Wu, Kuo-Jen, Bae, Eunkyung, Wang, Yu –Syuan, Chiang, Chia-Wen, Kuo, Li-Wei, Harvey, Brandon K., Greig, Nigel H., Wang, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013187/ https://www.ncbi.nlm.nih.gov/pubmed/32058974 http://dx.doi.org/10.1016/j.isci.2020.100866 |
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