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Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells

The effects of ascorbate on adult cell fate specification remain largely unknown. Using our stepwise and chemically defined system to derive lateral mesoderm progenitors from human pluripotent stem cells (hPSCs), we found that ascorbate increased the expression of mesenchymal stromal cell (MSC) mark...

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Detalles Bibliográficos
Autores principales: Liu, Tong Ming, Yildirim, Ege Deniz, Li, Pin, Fang, Hai Tong, Denslin, Vinitha, Kumar, Vibhor, Loh, Yuin Han, Lee, Eng Hin, Cool, Simon M., Teh, Bin Tean, Hui, James H., Lim, Bing, Shyh-Chang, Ng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013236/
https://www.ncbi.nlm.nih.gov/pubmed/32004493
http://dx.doi.org/10.1016/j.stemcr.2020.01.002

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