Activin A and BMP4 Signaling Expands Potency of Mouse Embryonic Stem Cells in Serum-Free Media

Inhibitors of Mek1/2 and Gsk3β, known as 2i, and, together with leukemia inhibitory factor, enhance the derivation of embryonic stem cells (ESCs) and promote ground-state pluripotency (2i/L-ESCs). However, recent reports show that prolonged Mek1/2 suppression impairs developmental potential of ESCs,...

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Detalles Bibliográficos
Autores principales: Wu, Baojiang, Li, Lin, Li, Bojiang, Gao, Junpeng, Chen, Yanglin, Wei, Mengyi, Yang, Zhiqing, Zhang, Baojing, Li, Shudong, Li, Kexin, Wang, Changshan, Surani, M. Azim, Li, Xihe, Tang, Fuchou, Bao, Siqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013251/
https://www.ncbi.nlm.nih.gov/pubmed/32032551
http://dx.doi.org/10.1016/j.stemcr.2020.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013251/
https://www.ncbi.nlm.nih.gov/pubmed/32032551
http://dx.doi.org/10.1016/j.stemcr.2020.01.004

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