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Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period

OBJECTIVE: During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone...

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Autor principal: Tharwat, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013289/
https://www.ncbi.nlm.nih.gov/pubmed/32099639
http://dx.doi.org/10.1155/2020/4064209
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author Tharwat, Mohamed
author_facet Tharwat, Mohamed
author_sort Tharwat, Mohamed
collection PubMed
description OBJECTIVE: During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone-specific alkaline phosphatase (b-ALP), and pyridinoline cross-links (PYD). METHOD: Blood samples were collected from fifteen female goats during the periparturient period 3 wk before expected parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition ( RESULTS: Compared to a value of 77.67 ± 47.6 ng/mL at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at CONCLUSION: The results of this study showed that the bone formation biomarkers (OC and b-ALP) did not change significantly during the periparturient period, while the bone resorption biomarker decreased significantly at parturition compared to 3 wk before and 3 wk after parturition. The significantly increased serum estrogen around parturition may have had a role in the increased bone resorption at this time.
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spelling pubmed-70132892020-02-25 Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period Tharwat, Mohamed Vet Med Int Research Article OBJECTIVE: During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone-specific alkaline phosphatase (b-ALP), and pyridinoline cross-links (PYD). METHOD: Blood samples were collected from fifteen female goats during the periparturient period 3 wk before expected parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition ( RESULTS: Compared to a value of 77.67 ± 47.6 ng/mL at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at CONCLUSION: The results of this study showed that the bone formation biomarkers (OC and b-ALP) did not change significantly during the periparturient period, while the bone resorption biomarker decreased significantly at parturition compared to 3 wk before and 3 wk after parturition. The significantly increased serum estrogen around parturition may have had a role in the increased bone resorption at this time. Hindawi 2020-01-31 /pmc/articles/PMC7013289/ /pubmed/32099639 http://dx.doi.org/10.1155/2020/4064209 Text en Copyright © 2020 Mohamed Tharwat. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tharwat, Mohamed
Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period
title Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period
title_full Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period
title_fullStr Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period
title_full_unstemmed Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period
title_short Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period
title_sort serum concentration of bone metabolism biomarkers in goats during the transition period
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013289/
https://www.ncbi.nlm.nih.gov/pubmed/32099639
http://dx.doi.org/10.1155/2020/4064209
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