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Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period
OBJECTIVE: During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013289/ https://www.ncbi.nlm.nih.gov/pubmed/32099639 http://dx.doi.org/10.1155/2020/4064209 |
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author | Tharwat, Mohamed |
author_facet | Tharwat, Mohamed |
author_sort | Tharwat, Mohamed |
collection | PubMed |
description | OBJECTIVE: During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone-specific alkaline phosphatase (b-ALP), and pyridinoline cross-links (PYD). METHOD: Blood samples were collected from fifteen female goats during the periparturient period 3 wk before expected parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition ( RESULTS: Compared to a value of 77.67 ± 47.6 ng/mL at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at CONCLUSION: The results of this study showed that the bone formation biomarkers (OC and b-ALP) did not change significantly during the periparturient period, while the bone resorption biomarker decreased significantly at parturition compared to 3 wk before and 3 wk after parturition. The significantly increased serum estrogen around parturition may have had a role in the increased bone resorption at this time. |
format | Online Article Text |
id | pubmed-7013289 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-70132892020-02-25 Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period Tharwat, Mohamed Vet Med Int Research Article OBJECTIVE: During the transition period, the animal experiences a series of nutritional, physiological, and social changes. The objective of the present study was to evaluate the influence of the periparturient period in goats on the serum concentrations of the bone biomarkers osteocalcin (OC), bone-specific alkaline phosphatase (b-ALP), and pyridinoline cross-links (PYD). METHOD: Blood samples were collected from fifteen female goats during the periparturient period 3 wk before expected parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition ( RESULTS: Compared to a value of 77.67 ± 47.6 ng/mL at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at T −3), within 12 h of parturition (T −3), within 12 h of parturition (P > 0.05). Compared to a value of 42.00 ± 19.50 U/L at CONCLUSION: The results of this study showed that the bone formation biomarkers (OC and b-ALP) did not change significantly during the periparturient period, while the bone resorption biomarker decreased significantly at parturition compared to 3 wk before and 3 wk after parturition. The significantly increased serum estrogen around parturition may have had a role in the increased bone resorption at this time. Hindawi 2020-01-31 /pmc/articles/PMC7013289/ /pubmed/32099639 http://dx.doi.org/10.1155/2020/4064209 Text en Copyright © 2020 Mohamed Tharwat. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Tharwat, Mohamed Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period |
title | Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period |
title_full | Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period |
title_fullStr | Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period |
title_full_unstemmed | Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period |
title_short | Serum Concentration of Bone Metabolism Biomarkers in Goats during the Transition Period |
title_sort | serum concentration of bone metabolism biomarkers in goats during the transition period |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013289/ https://www.ncbi.nlm.nih.gov/pubmed/32099639 http://dx.doi.org/10.1155/2020/4064209 |
work_keys_str_mv | AT tharwatmohamed serumconcentrationofbonemetabolismbiomarkersingoatsduringthetransitionperiod |