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Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice

OBJECTIVE: Obesity causes a variety of metabolic alterations that may contribute to abnormalities of the cardiac structure and function (obesity cardiomyopathy). In previous works, we have shown that pentamethylquercetin (PMQ) significantly improved metabolic disorders in obese mice and it inhibited...

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Detalles Bibliográficos
Autores principales: Du, Jingxia, He, Wei, Zhang, Cai, Wu, Jianzhao, Li, Zhi, Wang, Min, Feng, Shuying, Liang, Gaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013309/
https://www.ncbi.nlm.nih.gov/pubmed/32090078
http://dx.doi.org/10.1155/2020/3243906