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Analytical Method Development for Sodium Valproate through Chemical Derivatization

BACKGROUND: Sodium valproate has anticonvulsant activity and is structurally different to conventional antiepileptic drugs. The problem with valproic acid is the lack of a chromophore, which means that gas chromatography is the sole assay methodology. The introduction of benzoyl and phenyl groups to...

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Detalles Bibliográficos
Autores principales: Abualhasan, Murad, Odeh, Nihaya Wasif, Younis, Ghadeer Naser, Zeidan, Oyoun Fadel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013335/
https://www.ncbi.nlm.nih.gov/pubmed/32099545
http://dx.doi.org/10.1155/2020/5672183