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Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects

Epigenome editing is a promising technology, potentially allowing the stable reprogramming of gene expression profiles without alteration of the DNA sequence. Targeted DNA methylation has been successfully documented by many groups for silencing selected genes, but recent publications have raised co...

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Detalles Bibliográficos
Autores principales:	Hofacker, Daniel, Broche, Julian, Laistner, Laura, Adam, Sabrina, Bashtrykov, Pavel, Jeltsch, Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013458/ https://www.ncbi.nlm.nih.gov/pubmed/31941101 http://dx.doi.org/10.3390/ijms21020502

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