Cargando…

Biological Functions of HMGN Chromosomal Proteins

Chromatin plays a key role in regulating gene expression programs necessary for the orderly progress of development and for preventing changes in cell identity that can lead to disease. The high mobility group N (HMGN) is a family of nucleosome binding proteins that preferentially binds to chromatin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nanduri, Ravikanth, Furusawa, Takashi, Bustin, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013550/ https://www.ncbi.nlm.nih.gov/pubmed/31936777 http://dx.doi.org/10.3390/ijms21020449

Ejemplares similares

Multiple epigenetic factors co-localize with HMGN proteins in A-compartment chromatin
por: He, Bing, et al.
Publicado: (2022)

Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins
por: Nanduri, Ravikanth, et al.
Publicado: (2022)

Chromatin De-Compaction By The Nucleosomal Binding Protein HMGN5 Impairs Nuclear Sturdiness
por: Furusawa, Takashi, et al.
Publicado: (2015)

Binding of HMGN proteins to cell specific enhancers stabilizes cell identity
por: He, Bing, et al.
Publicado: (2018)

Metabolomics Reveals a Role for the Chromatin-Binding Protein HMGN5 in Glutathione Metabolism
por: Ciappio, Eric D., et al.
Publicado: (2014)

HMGN proteins modulate chromatin regulatory sites and gene expression during activation of naïve B cells
por: Zhang, Shaofei, et al.
Publicado: (2016)

H3K27ac nucleosomes facilitate HMGN localization at regulatory sites to modulate chromatin binding of transcription factors
por: Zhang, Shaofei, et al.
Publicado: (2022)

Nucleosome structural changes induced by binding of non-histone chromosomal proteins HMGN1 and HMGN2()
por: Shimahara, Hideto, et al.
Publicado: (2013)

Effects of HMGN variants on the cellular transcription profile
por: Rochman, Mark, et al.
Publicado: (2011)

Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers
por: Deng, Tao, et al.
Publicado: (2015)

Lysine succinylation on non-histone chromosomal protein HMG-17 (HMGN2) regulates nucleosomal DNA accessibility by disrupting the HMGN2–nucleosome association
por: Jing, Yihang, et al.
Publicado: (2021)

HMGN1 and 2 remodel core and linker histone tail domains within chromatin
por: Murphy, Kevin J., et al.
Publicado: (2017)

Human HMGN1 and HMGN2 are not required for transcription-coupled DNA repair
por: Apelt, Katja, et al.
Publicado: (2020)

Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression
por: Mowery, Cody T., et al.
Publicado: (2018)

Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation
por: Deng, Tao, et al.
Publicado: (2017)

HMGN1 Modulates Nucleosome Occupancy and DNase I Hypersensitivity at the CpG Island Promoters of Embryonic Stem Cells
por: Deng, Tao, et al.
Publicado: (2013)

Epigenetic Regulators of White Adipocyte Browning
por: Nanduri, Ravikanth
Publicado: (2021)

HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis
por: Eliason, Steven, et al.
Publicado: (2022)

Functional genomics of HMGN3a and SMARCAL1 in early mammalian embryogenesis
por: Uzun, Alper, et al.
Publicado: (2009)

Shaking up the silence: consequences of HMGN1 antagonizing PRC2 in the Down syndrome brain
por: Farley, Sean J., et al.
Publicado: (2022)

HMGN5 Silencing Suppresses Cell Biological Progression via AKT/MAPK Pathway in Human Glioblastoma Cells
por: Ma, Quanfeng, et al.
Publicado: (2020)

Nucleosome-binding protein HMGN2 exhibits antitumor activity in oral squamous cell carcinoma
por: HU, ANKANG, et al.
Publicado: (2014)

Exogenous HMGN2 inhibits the migration and invasion of osteosarcoma cell lines
por: Xu, Enjie, et al.
Publicado: (2020)

Chromosomal Proteins HMG-14 and HMG-17 Are Released from Mitotic Chromosomes and Imported into the Nucleus by Active Transport
por: Hock, Robert, et al.
Publicado: (1998)

HMGN1 enhances CRISPR-directed dual-function A-to-G and C-to-G base editing
por: Yang, Chao, et al.
Publicado: (2023)

Effect of HMGN2 on proliferation and apoptosis of MCF-7 breast cancer cells
por: Fan, Bo, et al.
Publicado: (2019)

Gain of chromosome 21 increases the propensity for P2RY8: :CRLF2 acute lymphoblastic leukemia via increased HMGN1 expression
por: Page, Elyse C., et al.
Publicado: (2023)

HMGN2, a new anti-tumor effector molecule of CD8(+) T cells
por: Su, Lin, et al.
Publicado: (2014)

HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways
por: Alam, Md Masud, et al.
Publicado: (2018)

MicroRNA-140-5p regulates osteosarcoma chemoresistance by targeting HMGN5 and autophagy
por: Meng, Yichen, et al.
Publicado: (2017)

Molecular Biology of the Cell, Sixth Edition; ISBN: 9780815344643; and Molecular Biology of the Cell, Sixth Edition, The Problems Book; ISBN 9780815344537
por: Bustin, Stephen
Publicado: (2015)

Expression of HMGB1 and HMGN2 in gingival tissues, GCF and PICF of periodontitis patients and peri-implantitis
por: Xie, Ping, et al.
Publicado: (2011)

miR-488 inhibits cell growth and metastasis in renal cell carcinoma by targeting HMGN5
por: Wei, Xin, et al.
Publicado: (2018)

HMGN2 regulates non‐tuberculous mycobacteria survival via modulation of M1 macrophage polarization
por: Wang, Xinyuan, et al.
Publicado: (2019)

The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation
por: Jain, Lekha, et al.
Publicado: (2023)

HMGN5 promotes IL-6-induced epithelial-mesenchymal transition of bladder cancer by interacting with Hsp27
por: Yao, Kun, et al.
Publicado: (2020)

miR-488 Inhibits Cell Growth and Metastasis in Renal Cell Carcinoma by Targeting HMGN5 [Retraction]
Publicado: (2021)

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 lysine 27 trimethylation
por: Lane, Andrew A., et al.
Publicado: (2014)

Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model
por: Garza-Manero, Sylvia, et al.
Publicado: (2019)

Acteoside alleviates UUO-induced inflammation and fibrosis by regulating the HMGN1/TLR4/TREM1 signaling pathway
por: Mao, Yan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l1oa7ir0p097lor29ad7ea63oi