Cargando…
The EGFR-ERK/JNK-CCL20 Pathway in Scratched Keratinocytes May Underpin Koebnerization in Psoriasis Patients
Epidermal keratinocytes represent a rich source of C-C motif chemokine 20 (CCL20) and recruit CCR6(+) interleukin (IL)-17A–producing T cells that are known to be pathogenic for psoriasis. A previous study revealed that scratch injury on keratinocytes upregulates CCL20 production, which is implicated...
Autores principales: | Furue, Kazuhisa, Ito, Takamichi, Tanaka, Yuka, Hashimoto-Hachiya, Akiko, Takemura, Masaki, Murata, Maho, Kido-Nakahara, Makiko, Tsuji, Gaku, Nakahara, Takeshi, Furue, Masutaka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013594/ https://www.ncbi.nlm.nih.gov/pubmed/31936670 http://dx.doi.org/10.3390/ijms21020434 |
Ejemplares similares
-
Scratching Counteracts IL-13 Signaling by Upregulating the Decoy Receptor IL-13Rα2 in Keratinocytes
por: Ulzii, Dugarmaa, et al.
Publicado: (2019) -
Interleukin-17A and Keratinocytes in Psoriasis
por: Furue, Masutaka, et al.
Publicado: (2020) -
Aryl Hydrocarbon Receptor Activation Downregulates IL-33 Expression in Keratinocytes via Ovo-Like 1
por: Tsuji, Gaku, et al.
Publicado: (2020) -
Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis
por: Tsuji, Gaku, et al.
Publicado: (2020) -
IL-4 Augments IL-31/IL-31 Receptor Alpha Interaction Leading to Enhanced Ccl 17 and Ccl 22 Production in Dendritic Cells: Implications for Atopic Dermatitis
por: Miake, Sho, et al.
Publicado: (2019)