Cargando…

Blood Co-Circulating Extracellular microRNAs and Immune Cell Subsets Associate with Type 1 Diabetes Severity

Immune cell subsets and microRNAs have been independently proposed as type 1 diabetes (T1D) diagnostic and/or prognostic biomarkers. Here, we aimed to analyze the relationships between peripheral blood circulating immune cell subsets, plasmatic microRNAs, and T1D. Blood samples were obtained from bo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garavelli, Silvia, Bruzzaniti, Sara, Tagliabue, Elena, Prattichizzo, Francesco, Di Silvestre, Dario, Perna, Francesco, La Sala, Lucia, Ceriello, Antonio, Mozzillo, Enza, Fattorusso, Valentina, Mauri, Pierluigi, Puca, Annibale A., Franzese, Adriana, Matarese, Giuseppe, Galgani, Mario, de Candia, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013659/ https://www.ncbi.nlm.nih.gov/pubmed/31940853 http://dx.doi.org/10.3390/ijms21020477

Ejemplares similares

Type 2 Diabetes: How Much of an Autoimmune Disease?
por: de Candia, Paola, et al.
Publicado: (2019)

CD4(+) T-Cell Activation Prompts Suppressive Function by Extracellular Vesicle-Associated MicroRNAs
por: Di Silvestre, Dario, et al.
Publicado: (2021)

T1D progression is associated with loss of CD3(+)CD56(+) regulatory T cells that control CD8(+) T cell effector functions
por: Terrazzano, Giuseppe, et al.
Publicado: (2020)

CD4(+) T Cell Defects in a Mulibrey Patient With Specific TRIM37 Mutations
por: Bruzzaniti, Sara, et al.
Publicado: (2020)

T Cells: Warriors of SARS-CoV-2 Infection
por: de Candia, Paola, et al.
Publicado: (2021)

Metabolism and Autoimmune Responses: The microRNA Connection
por: Colamatteo, Alessandra, et al.
Publicado: (2019)

One-hour plasma glucose combined with skin autofluorescence identifies subjects with pre-diabetes: the DIAPASON study
por: La Sala, Lucia, et al.
Publicado: (2020)

Meta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression
por: Galgani, Mario, et al.
Publicado: (2013)

Long-Term Follow-Up in a Girl with Cystic Fibrosis and Diabetes Since the First Year of Life
por: Fattorusso, Valentina, et al.
Publicado: (2017)

Effect of time and titer in convalescent plasma therapy for COVID-19
por: de Candia, Paola, et al.
Publicado: (2021)

The pleiotropic roles of leptin in metabolism, immunity, and cancer
por: de Candia, Paola, et al.
Publicado: (2021)

Diagnosis of congenital Hyperinsulinism can occur not only in infancy but also in later age: a new flow chart from a single center experience
por: Casertano, Alberto, et al.
Publicado: (2020)

Wolfram Syndrome Type 2: A Systematic Review of a Not Easily Identifiable Clinical Spectrum
por: Rosanio, Francesco Maria, et al.
Publicado: (2022)

Case Report: Ophthalmologic Evaluation Over a Long Follow-Up Time in a Patient With Wolfram Syndrome Type 2: Slowly Progressive Optic Neuropathy as a Possible Clinical Finding
por: Di Iorio, Valentina, et al.
Publicado: (2021)

NGS Analysis Revealed Digenic Heterozygous GCK and HNF1A Variants in a Child with Mild Hyperglycemia: A Case Report
por: Iafusco, Fernanda, et al.
Publicado: (2021)

An Overview of Hypoglycemia in Children Including a Comprehensive Practical Diagnostic Flowchart for Clinical Use
por: Casertano, Alberto, et al.
Publicado: (2021)

Doctor-Patient Relationship in Synchronous/Real-time Video-Consultations and In-Person Visits: An Investigation of the Perceptions of Young People with Type 1 Diabetes and Their Parents During the COVID-19 Pandemic
por: Troncone, Alda, et al.
Publicado: (2022)

Extracellular vesicles circulating in young organisms promote healthy longevity
por: Prattichizzo, Francesco, et al.
Publicado: (2019)

Glucose Derangements in Very Young Children With Cystic Fibrosis and Pancreatic Insufficiency
por: Mozzillo, Enza, et al.
Publicado: (2012)

Tackling the pillars of ageing to fight COVID-19
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

Cystic Fibrosis-Related Diabetes (CFRD): Overview of Associated Genetic Factors
por: Iafusco, Fernanda, et al.
Publicado: (2021)

Analysis of Corneal Deformation in Paediatric Patients Affected by Maturity Onset Diabetes of the Young Type 2
por: Lanza, Michele, et al.
Publicado: (2023)

Circulating microRNA-21 is an early predictor of ROS-mediated damage in subjects with high risk of developing diabetes and in drug-naïve T2D
por: La Sala, Lucia, et al.
Publicado: (2019)

Precocious Pseudo-Puberty in a 7-Year-Old Girl Due to Malignant Mixed Ovarian Germ Cell Tumor
por: Improda, Nicola, et al.
Publicado: (2023)

Pharmacological management of COVID-19 in type 2 diabetes
por: Ceriello, Antonio, et al.
Publicado: (2021)

Variability of risk factors and diabetes complications
por: Ceriello, Antonio, et al.
Publicado: (2021)

Celiac disease in type 1 diabetes mellitus
por: Camarca, Maria Erminia, et al.
Publicado: (2012)

Serum levels of SARS-CoV-2 nucleocapsid antigen associate with inflammatory status and disease severity in COVID-19 patients
por: Perna, Francesco, et al.
Publicado: (2021)

Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its cardiovascular complications
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

Diabetes outbreak during COVID19 lock-down in a prediabetic patient with cystic fibrosis long treated with glargine
por: Rosanio, Francesco Maria, et al.
Publicado: (2021)

Glucose-sensing microRNA-21 disrupts ROS homeostasis and impairs antioxidant responses in cellular glucose variability
por: La Sala, Lucia, et al.
Publicado: (2018)

Repurposing SGLT-2 Inhibitors to Target Aging: Available Evidence and Molecular Mechanisms
por: La Grotta, Rosalba, et al.
Publicado: (2022)

The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin functions as antioxidant on human endothelial cells exposed to chronic hyperglycemia and metabolic high-glucose memory
por: Pujadas, Gemma, et al.
Publicado: (2016)

An Italian case series' description of thiamine responsive megaloblastic anemia syndrome: importance of early diagnosis and treatment
por: Di Candia, Francesca, et al.
Publicado: (2023)

The “Metabolic Memory” Theory and the Early Treatment of Hyperglycemia in Prevention of Diabetic Complications
por: Testa, Roberto, et al.
Publicado: (2017)

“Inflammaging” as a Druggable Target: A Senescence-Associated Secretory Phenotype—Centered View of Type 2 Diabetes
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

Anti-inflammatory effect of SGLT-2 inhibitors via uric acid and insulin
por: La Grotta, Rosalba, et al.
Publicado: (2022)

A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients
por: Cattaneo, Monica, et al.
Publicado: (2017)

DPP-4 Inhibitors Have Different Effects on Endothelial Low-Grade Inflammation and on the M1-M2 Macrophage Polarization Under Hyperglycemic Conditions
por: De Nigris, Valeria, et al.
Publicado: (2021)

Optimal Prandial Timing of Insulin Bolus in Youths with Type 1 Diabetes: A Systematic Review
por: Mozzillo, Enza, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jc18mdqi0og7mtt9h040nkoag5