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Preferential Coupling of Dopamine D(2S) and D(2L) Receptor Isoforms with G(i1) and G(i2) Proteins—In Silico Study
The dopamine D(2) receptor belongs to rhodopsin-like G protein-coupled receptors (GPCRs) and it is an important molecular target for the treatment of many disorders, including schizophrenia and Parkinson’s disease. Here, computational methods were used to construct the full models of the dopamine D(...
Autores principales: | Żuk, Justyna, Bartuzi, Damian, Matosiuk, Dariusz, Kaczor, Agnieszka A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013695/ https://www.ncbi.nlm.nih.gov/pubmed/31936673 http://dx.doi.org/10.3390/ijms21020436 |
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