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Preferential Coupling of Dopamine D(2S) and D(2L) Receptor Isoforms with G(i1) and G(i2) Proteins—In Silico Study

The dopamine D(2) receptor belongs to rhodopsin-like G protein-coupled receptors (GPCRs) and it is an important molecular target for the treatment of many disorders, including schizophrenia and Parkinson’s disease. Here, computational methods were used to construct the full models of the dopamine D(...

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Detalles Bibliográficos
Autores principales: Żuk, Justyna, Bartuzi, Damian, Matosiuk, Dariusz, Kaczor, Agnieszka A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013695/
https://www.ncbi.nlm.nih.gov/pubmed/31936673
http://dx.doi.org/10.3390/ijms21020436

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