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Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K(2)P Channels
Two-pore domain potassium (K(2)P) channels maintain the cell’s background conductance by stabilizing the resting membrane potential. They assemble as dimers possessing four transmembrane helices in each subunit. K(2)P channels were crystallized in “up” and “down” states. The movements of the pore-li...
Autores principales: | Bustos, Daniel, Bedoya, Mauricio, Ramírez, David, Concha, Guierdy, Zúñiga, Leandro, Decher, Niels, Hernández-Rodríguez, Erix W., Sepúlveda, Francisco V., Martínez, Leandro, González, Wendy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013731/ https://www.ncbi.nlm.nih.gov/pubmed/31947679 http://dx.doi.org/10.3390/ijms21020532 |
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