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Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China

Background: Few studies have previously explored the relationship between hand, foot, and mouth disease (HFMD) and meteorological factors with the effect modification of air pollution, and these studies had inconsistent findings. We therefore applied a time-series analysis assessing the effects of t...

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Autores principales: Hao, Jiayuan, Yang, Zhiyi, Yang, Wenwen, Huang, Shuqiong, Tian, Liqiao, Zhu, Zhongmin, Lu, Yuanan, Xiang, Hao, Liu, Suyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013846/
https://www.ncbi.nlm.nih.gov/pubmed/31936369
http://dx.doi.org/10.3390/ijerph17020428
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author Hao, Jiayuan
Yang, Zhiyi
Yang, Wenwen
Huang, Shuqiong
Tian, Liqiao
Zhu, Zhongmin
Lu, Yuanan
Xiang, Hao
Liu, Suyang
author_facet Hao, Jiayuan
Yang, Zhiyi
Yang, Wenwen
Huang, Shuqiong
Tian, Liqiao
Zhu, Zhongmin
Lu, Yuanan
Xiang, Hao
Liu, Suyang
author_sort Hao, Jiayuan
collection PubMed
description Background: Few studies have previously explored the relationship between hand, foot, and mouth disease (HFMD) and meteorological factors with the effect modification of air pollution, and these studies had inconsistent findings. We therefore applied a time-series analysis assessing the effects of temperature and humidity on the incidence of HFMD in Wuhan, China to deepen our understanding of the relationship between meteorological factors and the risk of HFMD. Methods: Daily HFMD cases were retrieved from Hubei Provincial Center for Disease Control and Prevention from 1 February 2013 to 31 January 2017. Daily meteorological data including 24 h average temperature, relative humidity, wind velocity, and atmospheric pressure were obtained from Hubei Meteorological Bureau. Data on Air pollution was collected from 10 national air-monitoring stations in Wuhan city. We adopted a distributed lag non-linear model (DLNM) combined with Poisson regression and time-series analysis to estimate the effects of temperature and relative humidity on the incidence HFMD. Results: We found that the association between temperature and HFMD incidence was non-linear, exhibiting an approximate “M” shape with two peaks occurring at 2.3 °C (RR = 1.760, 95% CI: 1.218–2.542) and 27.9 °C (RR = 1.945, 95% CI: 1.570–2.408), respectively. We observed an inverted “V” shape between relative humidity and HFMD. The risk of HFMD reached a maximum value at a relative humidity of 89.2% (RR = 1.553, 95% CI: 1.322–1.824). The largest delayed cumulative effects occurred at lag 6 for temperature and lag 13 for relative humidity. Conclusions: The non-linear relationship between meteorological factors and the incidence of HFMD on different lag days could be used in the early targeted warning system of infectious diseases, reducing the possible outbreaks and burdens of HFMD among sensitive populations.
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spelling pubmed-70138462020-03-09 Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China Hao, Jiayuan Yang, Zhiyi Yang, Wenwen Huang, Shuqiong Tian, Liqiao Zhu, Zhongmin Lu, Yuanan Xiang, Hao Liu, Suyang Int J Environ Res Public Health Article Background: Few studies have previously explored the relationship between hand, foot, and mouth disease (HFMD) and meteorological factors with the effect modification of air pollution, and these studies had inconsistent findings. We therefore applied a time-series analysis assessing the effects of temperature and humidity on the incidence of HFMD in Wuhan, China to deepen our understanding of the relationship between meteorological factors and the risk of HFMD. Methods: Daily HFMD cases were retrieved from Hubei Provincial Center for Disease Control and Prevention from 1 February 2013 to 31 January 2017. Daily meteorological data including 24 h average temperature, relative humidity, wind velocity, and atmospheric pressure were obtained from Hubei Meteorological Bureau. Data on Air pollution was collected from 10 national air-monitoring stations in Wuhan city. We adopted a distributed lag non-linear model (DLNM) combined with Poisson regression and time-series analysis to estimate the effects of temperature and relative humidity on the incidence HFMD. Results: We found that the association between temperature and HFMD incidence was non-linear, exhibiting an approximate “M” shape with two peaks occurring at 2.3 °C (RR = 1.760, 95% CI: 1.218–2.542) and 27.9 °C (RR = 1.945, 95% CI: 1.570–2.408), respectively. We observed an inverted “V” shape between relative humidity and HFMD. The risk of HFMD reached a maximum value at a relative humidity of 89.2% (RR = 1.553, 95% CI: 1.322–1.824). The largest delayed cumulative effects occurred at lag 6 for temperature and lag 13 for relative humidity. Conclusions: The non-linear relationship between meteorological factors and the incidence of HFMD on different lag days could be used in the early targeted warning system of infectious diseases, reducing the possible outbreaks and burdens of HFMD among sensitive populations. MDPI 2020-01-08 2020-01 /pmc/articles/PMC7013846/ /pubmed/31936369 http://dx.doi.org/10.3390/ijerph17020428 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hao, Jiayuan
Yang, Zhiyi
Yang, Wenwen
Huang, Shuqiong
Tian, Liqiao
Zhu, Zhongmin
Lu, Yuanan
Xiang, Hao
Liu, Suyang
Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China
title Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China
title_full Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China
title_fullStr Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China
title_full_unstemmed Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China
title_short Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China
title_sort impact of ambient temperature and relative humidity on the incidence of hand-foot-mouth disease in wuhan, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013846/
https://www.ncbi.nlm.nih.gov/pubmed/31936369
http://dx.doi.org/10.3390/ijerph17020428
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