Multiple Cell Signalling Pathways of Human Proinsulin C-Peptide in Vasculopathy Protection

A major hallmark of diabetes is a constant high blood glucose level (hyperglycaemia), resulting in endothelial dysfunction. Transient or prolonged hyperglycemia can cause diabetic vasculopathy, a secondary systemic damage. C-Peptide is a product of cleavage of proinsulin by a serine protease that oc...

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Detalles Bibliográficos
Autores principales: Souto, Selma B., Campos, Joana R., Fangueiro, Joana F., Silva, Amélia M., Cicero, Nicola, Lucarini, Massimo, Durazzo, Alessandra, Santini, Antonello, Souto, Eliana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013900/
https://www.ncbi.nlm.nih.gov/pubmed/31963760
http://dx.doi.org/10.3390/ijms21020645

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