Cargando…

Progress of Induced Pluripotent Stem Cell Technologies to Understand Genetic Epilepsy

The study of the pathomechanisms by which gene mutations lead to neurological diseases has benefit from several cellular and animal models. Recently, induced Pluripotent Stem Cell (iPSC) technologies have made possible the access to human neurons to study nervous system disease-related mechanisms, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sterlini, Bruno, Fruscione, Floriana, Baldassari, Simona, Benfenati, Fabio, Zara, Federico, Corradi, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013950/ https://www.ncbi.nlm.nih.gov/pubmed/31940887 http://dx.doi.org/10.3390/ijms21020482

Ejemplares similares

The PRRT2 knockout mouse recapitulates the neurological diseases associated with PRRT2 mutations
por: Michetti, Caterina, et al.
Publicado: (2017)

PRRT2 controls neuronal excitability by negatively modulating Na(+) channel 1.2/1.6 activity
por: Fruscione, Floriana, et al.
Publicado: (2018)

Vesicular Glutamate Release from Feeder-FreehiPSC-Derived Neurons
por: Baldassari, Simona, et al.
Publicado: (2022)

A Push–Pull Mechanism Between PRRT2 and β4-subunit Differentially Regulates Membrane Exposure and Biophysical Properties of NaV1.2 Sodium Channels
por: Valente, Pierluigi, et al.
Publicado: (2022)

A Novel Topology of Proline-rich Transmembrane Protein 2 (PRRT2): HINTS FOR AN INTRACELLULAR FUNCTION AT THE SYNAPSE
por: Rossi, Pia, et al.
Publicado: (2016)

Progress in the molecular mechanisms of genetic epilepsies using patient‐induced pluripotent stem cells
por: Zhou, Ruijiao, et al.
Publicado: (2018)

Hyccin, the Molecule Mutated in the Leukodystrophy Hypomyelination and Congenital Cataract (HCC), Is a Neuronal Protein
por: Gazzerro, Elisabetta, et al.
Publicado: (2012)

Clinical and Genetic Features in Patients With Reflex Bathing Epilepsy
por: Accogli, Andrea, et al.
Publicado: (2021)

Brain Organoids as Model Systems for Genetic Neurodevelopmental Disorders
por: Baldassari, Simona, et al.
Publicado: (2020)

The intramembrane COOH-terminal domain of PRRT2 regulates voltage-dependent Na(+) channels
por: Franchi, Francesca, et al.
Publicado: (2023)

An interaction between PRRT2 and Na(+)/K(+) ATPase contributes to the control of neuronal excitability
por: Sterlini, Bruno, et al.
Publicado: (2021)

PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery
por: Valente, Pierluigi, et al.
Publicado: (2016)

Technological Progress in Generation of Induced Pluripotent Stem Cells for Clinical Applications
por: Oh, Seung-Ick, et al.
Publicado: (2012)

PRRT2 modulates presynaptic Ca(2+) influx by interacting with P/Q-type channels
por: Ferrante, Daniele, et al.
Publicado: (2021)

Human-Induced Pluripotent Stem Cell Technology and Cardiomyocyte Generation: Progress and Clinical Applications
por: Di Baldassarre, Angela, et al.
Publicado: (2018)

Advances in Induced Pluripotent Stem Cell Technologies
por: Pal, Rajarshi, et al.
Publicado: (2012)

Pluripotent Stem Cells: Current Understanding and Future Directions
por: Romito, Antonio, et al.
Publicado: (2016)

Transcranial magnetic stimulation as a tool to understand genetic conditions associated with epilepsy
por: Silvennoinen, Katri, et al.
Publicado: (2020)

Current understanding of genomic stability maintenancein pluripotent stem cells: Genomic stability maintenance in pluripotent stem cells
por: Zheng, Ping
Publicado: (2022)

Personalized Medicine Using Cutting Edge Technologies for Genetic Epilepsies
por: Garcia-Rosa, Sheila, et al.
Publicado: (2021)

Human In Vitro Models of Epilepsy Using Embryonic and Induced Pluripotent Stem Cells
por: Javaid, Muhammad Shahid, et al.
Publicado: (2022)

Mitochondrial Medicine: Genetic Underpinnings and Disease Modeling Using Induced Pluripotent Stem Cell Technology
por: Kargaran, Parisa K., et al.
Publicado: (2021)

Bringing Induced Pluripotent Stem Cell Technology to the Bedside
por: Karagiannis, Peter, et al.
Publicado: (2018)

Targeting Alternative Splicing as a Potential Therapy for Episodic Ataxia Type 2
por: Jaudon, Fanny, et al.
Publicado: (2020)

PRRT2, a network stability gene
por: Michetti, Caterina, et al.
Publicado: (2017)

The Cutting Edge of Disease Modeling: Synergy of Induced Pluripotent Stem Cell Technology and Genetically Encoded Biosensors
por: Valetdinova, Kamila R., et al.
Publicado: (2021)

Induced pluripotent stem cells from patients with focal cortical dysplasia and refractory epilepsy
por: Marinowic, Daniel Rodrigo, et al.
Publicado: (2017)

Understanding Epilepsy
por: Hopkins, Anthony
Publicado: (1989)

Stem Cell Technology in Cardiac Regeneration: A Pluripotent Stem Cell Promise
por: Duelen, Robin, et al.
Publicado: (2017)

Induced pluripotent stem cell technology for dissecting the cancer epigenome
por: Semi, Katsunori, et al.
Publicado: (2015)

Advances in Pluripotent Stem Cells: History, Mechanisms, Technologies, and Applications
por: Liu, Gele, et al.
Publicado: (2019)

Pluripotent stem cells for Parkinson's disease: progress and challenges
por: Zeng, Xianmin, et al.
Publicado: (2013)

G1-phase progression in pluripotent stem cells
por: ter Huurne, Menno, et al.
Publicado: (2021)

Progress and Prospects of Gene Editing in Pluripotent Stem Cells
por: Zhang, Zhenwu, et al.
Publicado: (2023)

Emerging Role of the Autophagy/Lysosomal Degradative Pathway in Neurodevelopmental Disorders With Epilepsy
por: Fassio, Anna, et al.
Publicado: (2020)

Using Pluripotent Stem Cells to Understand Normal and Leukemic Hematopoietic Development
por: Bigas, Anna, et al.
Publicado: (2022)

Mesenchymal Stem Cell-derived Neural Progenitor Cells in Progressive Multiple Sclerosis: Great Expectations
por: Baldassari, Laura E., et al.
Publicado: (2018)

International Veterinary Epilepsy Task Force’s current understanding of idiopathic epilepsy of genetic or suspected genetic origin in purebred dogs
por: Hülsmeyer, Velia-Isabel, et al.
Publicado: (2015)

Rejuvenated Stem/Progenitor Cells for Cartilage Repair Using the Pluripotent Stem Cell Technology
por: Nakayama, Naoki, et al.
Publicado: (2021)

Recent technological updates and clinical applications of induced pluripotent stem cells
por: Diecke, Sebastian, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5udul7jbtomg7k498pgqt1pge0