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Characterization in Dual Activation by Oxaliplatin, a Platinum-Based Chemotherapeutic Agent of Hyperpolarization-Activated Cation and Electroporation-Induced Currents

Oxaliplatin (OXAL) is regarded as a platinum-based anti-neoplastic agent. However, its perturbations on membrane ionic currents in neurons and neuroendocrine or endocrine cells are largely unclear, though peripheral neuropathy has been noted during its long-term administration. In this study, we inv...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Ting, Gao, Zi-Han, Li, Shih-Wei, Liu, Ping-Yen, Lo, Yi-Ching, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014111/
https://www.ncbi.nlm.nih.gov/pubmed/31936301
http://dx.doi.org/10.3390/ijms21020396