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SV40 Transfected Human Anterior Cruciate Ligament Derived Ligamentocytes—Suitable as a Human in Vitro Model for Ligament Reconstruction?

Cultured human primary cells have a limited lifespan undergoing dedifferentiation or senescence. Anterior cruciate ligaments (ACL) are hypocellular but tissue engineering (TE) requires high cell numbers. Simian virus (SV) 40 tumor (T) antigen expression could extend the lifespan of cells. This study...

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Detalles Bibliográficos
Autores principales:	Schulze-Tanzil, Gundula, Arnold, Philipp, Gögele, Clemens, Hahn, Judith, Breier, Annette, Meyer, Michael, Kohl, Benjamin, Schröpfer, Michaela, Schwarz, Silke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014138/ https://www.ncbi.nlm.nih.gov/pubmed/31963350 http://dx.doi.org/10.3390/ijms21020593

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