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BCL-xL, a Mitochondrial Protein Involved in Successful Aging: From C. elegans to Human Centenarians

B-Cell Lymphoma-extra-large (BCL-xL) is involved in longevity and successful aging, which indicates a role for BCL-xL in cell survival pathway regulation. Beyond its well described role as an inhibitor of apoptosis by preventing cytochrome c release, BCL-xL has also been related, indirectly, to auto...

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Detalles Bibliográficos
Autores principales: Borrás, Consuelo, Mas-Bargues, Cristina, Román-Domínguez, Aurora, Sanz-Ros, Jorge, Gimeno-Mallench, Lucia, Inglés, Marta, Gambini, Juan, Viña, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014191/
https://www.ncbi.nlm.nih.gov/pubmed/31936510
http://dx.doi.org/10.3390/ijms21020418