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Editing DNA Methylation in Mammalian Embryos

DNA methylation in mammals is essential for numerous biological functions, such as ensuring chromosomal stability, genomic imprinting, and X-chromosome inactivation through transcriptional regulation. Gene knockout of DNA methyltransferases and demethylation enzymes has made significant contribution...

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Detalles Bibliográficos
Autores principales:	Yamazaki, Taiga, Hatano, Yu, Taniguchi, Ryoya, Kobayashi, Noritada, Yamagata, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014263/ https://www.ncbi.nlm.nih.gov/pubmed/31963664 http://dx.doi.org/10.3390/ijms21020637

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