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Topical Therapy with Antisense Tumor Necrosis Factor Alpha Using Novel β-Glucan-Based Drug Delivery System Ameliorates Intestinal Inflammation

Anti-tumor necrosis factor alpha (TNF-α) antibodies are effective in patients with inflammatory bowel disease (IBD). However, the effect is not optimal because a sufficient concentration of antibodies cannot be maintained at the site of inflammation. Thus, a macromolecular complex was developed with...

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Detalles Bibliográficos
Autores principales:	Sakisaka, Hideto, Takedatsu, Hidetoshi, Mitsuyama, Keiichi, Mochizuki, Shinichi, Sakurai, Kazuo, Sakisaka, Shotaro, Hirai, Fumihito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014273/ https://www.ncbi.nlm.nih.gov/pubmed/31968666 http://dx.doi.org/10.3390/ijms21020683

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