Cargando…

CRISPR/Cas9-Mediated TERT Disruption in Cancer Cells

Mammalian telomere lengths are primarily regulated by telomerase, a ribonucleoprotein consisting of a reverse transcriptase (TERT) and an RNA subunit (TERC). TERC is constitutively expressed in all cells, whereas TERT expression is temporally and spatially regulated, such that in most adult somatic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Luan, Zhao, Changzhi, Song, Jun, Ma, Linyuan, Ruan, Jinxue, Xia, Xiaofeng, Chen, Y. Eugene, Zhang, Jifeng, Ma, Peter X., Xu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014288/ https://www.ncbi.nlm.nih.gov/pubmed/31963842 http://dx.doi.org/10.3390/ijms21020653

Ejemplares similares

MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits
por: Ma, Linyuan, et al.
Publicado: (2020)

Delivery of CRISPR/Cas9 Plasmid DNA by Hyperbranched Polymeric Nanoparticles Enables Efficient Gene Editing
por: Xiu, Kemao, et al.
Publicado: (2022)

Phenotypes of CF rabbits generated by CRISPR/Cas9-mediated disruption of the CFTR gene
por: Xu, Jie, et al.
Publicado: (2021)

Efficient homology-directed gene editing by CRISPR/Cas9 in human stem and primary cells using tube electroporation
por: Xu, Xiaoyun, et al.
Publicado: (2018)

RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
por: Song, Jun, et al.
Publicado: (2016)

Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology
por: Han, Xiaosong, et al.
Publicado: (2020)

CRISPR/Cas9 ribonucleoprotein-mediated knockin generation in hTERT-RPE1 cells
por: Ghetti, Sabrina, et al.
Publicado: (2021)

CRISPR-Cas9-Mediated Cytosine Base Editing Screen for the Functional Assessment of CALR Intron Variants in Japanese Encephalitis Virus Replication
por: Xiong, Youcai, et al.
Publicado: (2023)

CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination
por: Herskovitz, Jonathan, et al.
Publicado: (2021)

Recyclable CRISPR/Cas9 mediated gene disruption and deletions in Histoplasma
por: Joehnk, Bastian, et al.
Publicado: (2023)

Highly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigs
por: Ruan, Jinxue, et al.
Publicado: (2015)

Development of CRISPR/Cas9-mediated gene disruption systems in Giardia lamblia
por: Lin, Zi-Qi, et al.
Publicado: (2019)

Recent Advances in Improving Gene-Editing Specificity through CRISPR–Cas9 Nuclease Engineering
por: Huang, Xiaoqiang, et al.
Publicado: (2022)

CRISPR-Cas9-Mediated Single-Gene and Gene Family Disruption in Trypanosoma cruzi
por: Peng, Duo, et al.
Publicado: (2014)

Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis
por: Horáčková, Vendula, et al.
Publicado: (2022)

CRISPR/Cas9-mediated Serine protease 2 disruption induces male sterility in Spodoptera litura
por: Bi, Honglun, et al.
Publicado: (2022)

CRISPR/Cas9-Mediated Disruption of the lef8 and lef9 to Inhibit Nucleopolyhedrovirus Replication in Silkworms
por: Liu, Yujia, et al.
Publicado: (2022)

CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation
por: Wu, Zhi-Jie, et al.
Publicado: (2018)

CRISPR/Cas9‐mediated resistance to cauliflower mosaic virus
por: Liu, Haijie, et al.
Publicado: (2018)

Targeted gene disruption in Xenopus laevis using CRISPR/Cas9
por: Wang, Fengqin, et al.
Publicado: (2015)

CRISPR/Cas9-mediated targeted chromosome elimination
por: Zuo, Erwei, et al.
Publicado: (2017)

CRISPR/Cas9 Mediated Disruption of Seminal Fluid Protein Sfp62 Induces Male Sterility in Bombyx mori
por: Xu, Xia, et al.
Publicado: (2022)

CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
por: Liang, Puping, et al.
Publicado: (2015)

CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients
por: Su, Shu, et al.
Publicado: (2016)

CRISPR-Cas9-Mediated Genome Editing in Leishmania donovani
por: Zhang, Wen-Wei, et al.
Publicado: (2015)

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
por: Zuckermann, Marc, et al.
Publicado: (2015)

CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X
por: Karimova, Madina, et al.
Publicado: (2015)

CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells for adoptive therapy
por: Su, Shu, et al.
Publicado: (2015)

Alteration of sheep coat color pattern by disruption of ASIP gene via CRISPR Cas9
por: Zhang, Xuemei, et al.
Publicado: (2017)

CRISPR/Cas9 Mediates Efficient Conditional Mutagenesis in Drosophila
por: Xue, Zhaoyu, et al.
Publicado: (2014)

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
por: Ebina, Hirotaka, et al.
Publicado: (2013)

Comparison of CRISPR–Cas9 Tools for Transcriptional Repression and Gene Disruption in the BEVS
por: Bruder, Mark R., et al.
Publicado: (2021)

Comparison of gene disruption induced by cytosine base editing‐mediated iSTOP with CRISPR/Cas9‐mediated frameshift
por: Dang, Lu, et al.
Publicado: (2020)

Corrigendum: CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients
por: Su, Shu, et al.
Publicado: (2017)

Applications of CRISPR-Cas9 mediated genome engineering
por: Yang, Xiao
Publicado: (2015)

CRISPR/Cas9-mediated viral interference in plants
por: Ali, Zahir, et al.
Publicado: (2015)

CRISPR-Cas9-Mediated Mutagenesis: Mind the Gap?
por: Teboul, Lydia, et al.
Publicado: (2018)

CRISPR/Cas9-mediated targeted mutagenesis in grape
por: Nakajima, Ikuko, et al.
Publicado: (2017)

Direct evidence of CRISPR-Cas9-mediated mitochondrial genome editing
por: Bi, Rui, et al.
Publicado: (2022)

CRISPR/Cas9-mediated gene knockin in the hydroid Hydractinia symbiolongicarpus
por: Sanders, Steven M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a9499gi0564hj1rjkik038l5sp