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Metformin Mitigates Nickel-Elicited Angiopoietin-Like Protein 4 Expression via HIF-1α for Lung Tumorigenesis

Nickel (Ni), which is a carcinogenic workplace hazard, increases the risk of lung cancer. Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine that is involved in both angiogenesis and metastasis, but its role in lung cancer is still not clear. In this study, we assessed the role of A...

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Detalles Bibliográficos
Autores principales: Kang, Yu-Ting, Hsu, Wen-Cheng, Ou, Chu-Chyn, Tai, Hui-Chun, Hsu, Hui-Ting, Yeh, Kun-Tu, Ko, Jiunn-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014330/
https://www.ncbi.nlm.nih.gov/pubmed/31963541
http://dx.doi.org/10.3390/ijms21020619