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Molecular and Regulatory Mechanisms of Desensitization and Resensitization of GABA(A) Receptors with a Special Reference to Propofol/Barbiturate
It is known that desensitization of GABA(A) receptor (GABA(A)R)-mediated currents is paradoxically correlated with the slowdown of their deactivation, i.e., resensitization. It has been shown that an upregulation of calcineurin enhances the desensitization of GABA(A)R-mediated currents but paradoxic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014398/ https://www.ncbi.nlm.nih.gov/pubmed/31952324 http://dx.doi.org/10.3390/ijms21020563 |