Cargando…

Cyp2j5-Gene Deletion Affects on Acetylcholine and Adenosine-Induced Relaxation in Mice: Role of Angiotensin-II and CYP-Epoxygenase Inhibitor

Previously, we showed vascular endothelial overexpression of human-CYP2J2 enhances coronary reactive hyperemia in Tie2-CYP2J2 Tr mice, and eNOS(−/−) mice had overexpression of CYP2J-epoxygenase with adenosine A(2A) receptor-induced enhance relaxation, but we did not see the response in CYP2J-epoxyge...

Descripción completa

Detalles Bibliográficos
Autores principales: Agba, Stephanie, Hanif, Ahmad, Edin, Matthew L., Zeldin, Darryl C., Nayeem, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014568/
https://www.ncbi.nlm.nih.gov/pubmed/32116704
http://dx.doi.org/10.3389/fphar.2020.00027