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miR-124 and miR-203 synergistically inactivate EMT pathway via coregulation of ZEB2 in clear cell renal cell carcinoma (ccRCC)

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is one of the most aggressive urological malignancies. MicroRNAs (miRNAs) are post-transcriptional gene regulators in tumor pathophysiology. As miRNAs exert cooperative repressive effects on target genes, studying the miRNA synergism is important t...

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Detalles Bibliográficos
Autores principales: Chen, Jiajia, Zhong, Yuqing, Li, Liangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014595/
https://www.ncbi.nlm.nih.gov/pubmed/32046742
http://dx.doi.org/10.1186/s12967-020-02242-x