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Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis

BACKGROUND: Atypical antipsychotic agents, such as clozapine, are used to treat schizophrenia and other psychiatric disorders by a mechanism that is believed to involve modulating the immune system. Multiple sclerosis is an immune-mediated neurological disease, and recently, clozapine was shown to r...

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Detalles Bibliográficos
Autores principales: Robichon, Katharina, Patel, Vimal, Connor, Bronwen, La Flamme, Anne Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014621/
https://www.ncbi.nlm.nih.gov/pubmed/32050980
http://dx.doi.org/10.1186/s12974-020-01733-4

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