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JCPyV NCCR analysis in PML patients with different risk factors: exploring common rearrangements as essential changes for neuropathogenesis

BACKGROUND: During severe immunosuppression or treatment with specific biological drugs, human polyomavirus JC (JCPyV) may establish a lytic infection in oligodendrocytes, leading to progressive multifocal leukoencephalopathy (PML). Beyond AIDS, which represents the most common predisposing conditio...

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Detalles Bibliográficos
Autores principales: Ciardi, Maria Rosa, Zingaropoli, Maria Antonella, Iannetta, Marco, Prezioso, Carla, Perri, Valentina, Pasculli, Patrizia, Lichtner, Miriam, d’Ettorre, Gabriella, Altieri, Marta, Conte, Antonella, Pietropaolo, Valeria, Mastroianni, Claudio Maria, Vullo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014659/
https://www.ncbi.nlm.nih.gov/pubmed/32046748
http://dx.doi.org/10.1186/s12985-020-1295-5