Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019

The Finnish new variant of Chlamydia trachomatis (FI-nvCT) is escaping diagnostics in Finland, Norway and Sweden. We have developed and validated an Aptima-format nucleic acid amplification test (NAAT) designed specifically to detect the FI-nvCT. This NAAT has high sensitivity (100%) and specificity...

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Autores principales: Weinbaum, Barbara, Williams, Analee, Hadad, Ronza, Vinluan, Bryan, Puolakkainen, Mirja, Unemo, Magnus, Getman, Damon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014671/
https://www.ncbi.nlm.nih.gov/pubmed/32046818
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.5.2000038
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author Weinbaum, Barbara
Williams, Analee
Hadad, Ronza
Vinluan, Bryan
Puolakkainen, Mirja
Unemo, Magnus
Getman, Damon
author_facet Weinbaum, Barbara
Williams, Analee
Hadad, Ronza
Vinluan, Bryan
Puolakkainen, Mirja
Unemo, Magnus
Getman, Damon
author_sort Weinbaum, Barbara
collection PubMed
description The Finnish new variant of Chlamydia trachomatis (FI-nvCT) is escaping diagnostics in Finland, Norway and Sweden. We have developed and validated an Aptima-format nucleic acid amplification test (NAAT) designed specifically to detect the FI-nvCT. This NAAT has high sensitivity (100%) and specificity (100%) for the FI-nvCT strain, enabling further investigation of the geographic distribution, prevalence and transmission of this diagnostic-escape mutant in screening populations in Europe.
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spelling pubmed-70146712020-02-25 Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019 Weinbaum, Barbara Williams, Analee Hadad, Ronza Vinluan, Bryan Puolakkainen, Mirja Unemo, Magnus Getman, Damon Euro Surveill Rapid Communication The Finnish new variant of Chlamydia trachomatis (FI-nvCT) is escaping diagnostics in Finland, Norway and Sweden. We have developed and validated an Aptima-format nucleic acid amplification test (NAAT) designed specifically to detect the FI-nvCT. This NAAT has high sensitivity (100%) and specificity (100%) for the FI-nvCT strain, enabling further investigation of the geographic distribution, prevalence and transmission of this diagnostic-escape mutant in screening populations in Europe. European Centre for Disease Prevention and Control (ECDC) 2020-02-06 /pmc/articles/PMC7014671/ /pubmed/32046818 http://dx.doi.org/10.2807/1560-7917.ES.2020.25.5.2000038 Text en This article is copyright of the authors or their affiliated institutions, 2020. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Weinbaum, Barbara
Williams, Analee
Hadad, Ronza
Vinluan, Bryan
Puolakkainen, Mirja
Unemo, Magnus
Getman, Damon
Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019
title Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019
title_full Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019
title_fullStr Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019
title_full_unstemmed Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019
title_short Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019
title_sort validation of an aptima-format finnish new variant of chlamydia trachomatis (fi-nvct) surveillance assay, 2019
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014671/
https://www.ncbi.nlm.nih.gov/pubmed/32046818
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.5.2000038
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