A toxicogenomic approach for the risk assessment of the food contaminant acetamide

Acetamide (CAS 60-35-5) is detected in common foods. Chronic rodent bioassays led to its classification as a group 2B possible human carcinogen due to the induction of liver tumors in rats. We used a toxicogenomics approach in Wistar rats gavaged daily for 7 or 28 days at doses of 300 to 1500 mg/kg/...

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Detalles Bibliográficos
Autores principales: Nault, Rance, Bals, Bryan, Teymouri, Farzaneh, Black, Michael B., Andersen, Melvin E., McMullen, Patrick D., Krishnan, Seetha, Kuravadi, Nagesh, Paul, Neetha, Kumar, Santhosh, Kannan, Kamala, Jayachandra, K.C., Alagappan, Lakshmanan, Patel, Bhavesh Dhirajlal, Bogen, Kenneth T., Gollapudi, Bhaskar B., Klaunig, James E., Zacharewski, Tim R., Bringi, Venkataraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014822/
https://www.ncbi.nlm.nih.gov/pubmed/31881176
http://dx.doi.org/10.1016/j.taap.2019.114872

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