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Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue
OBJECTIVE: One of the possible ways of changing human health might be through the oral mucosa. One of tongue disorders is geographic tongue (GT), which classic manifestation is an area of erythema, with atrophy of filiform papillae of the tongue, surrounded by a serpiginous, white, hyperkeratotic bo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014838/ https://www.ncbi.nlm.nih.gov/pubmed/32110568 http://dx.doi.org/10.4103/jfmpc.jfmpc_375_19 |
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author | Rezaei, Fatemeh Fatholahi, Saeedeh Rezaei, Farzad |
author_facet | Rezaei, Fatemeh Fatholahi, Saeedeh Rezaei, Farzad |
author_sort | Rezaei, Fatemeh |
collection | PubMed |
description | OBJECTIVE: One of the possible ways of changing human health might be through the oral mucosa. One of tongue disorders is geographic tongue (GT), which classic manifestation is an area of erythema, with atrophy of filiform papillae of the tongue, surrounded by a serpiginous, white, hyperkeratotic border. Saliva is a rich source of antioxidant and fulfills an important role in maintaining the normal function of the oral cavity. The purpose of the present study was to investigate the status of salivary antioxidant and immunoglobulin E in patients with GT and healthy people. MATERIALS AND METHODS: In this case-control study, samples were gathered from high school students in three municipal regions of Kermanshah, Iran by using multistage random cluster sampling method. The samples included 30 patients with GT (15 men and 15 women with the mean age of 17.6 ± 0.72) and 30 healthy volunteers (15 men and 15 women with the mean age of 17.1 ± 0.61). Saliva samples were collected through standard method, and total antioxidant capacity (TAC), catalase (CAT), and salivary immunoglobulin E were measured. RESULTS: In patients with GT, unstimulated salivary shows increased level of immunoglobulin compared with that of control group (P = 0.013). However, there was no significant relationship between control and GT patient groups regarding TAC of saliva (P = 0.91) and CAT (P = 0.83). CONCLUSION: It seems that the activity of CAT enzyme and TAC of saliva does not play primary role in the pathogenesis of GT. However, the level of immunoglobulin E present in saliva can function as an indicator of increased sensitivity in GT. |
format | Online Article Text |
id | pubmed-7014838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-70148382020-02-27 Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue Rezaei, Fatemeh Fatholahi, Saeedeh Rezaei, Farzad J Family Med Prim Care Original Article OBJECTIVE: One of the possible ways of changing human health might be through the oral mucosa. One of tongue disorders is geographic tongue (GT), which classic manifestation is an area of erythema, with atrophy of filiform papillae of the tongue, surrounded by a serpiginous, white, hyperkeratotic border. Saliva is a rich source of antioxidant and fulfills an important role in maintaining the normal function of the oral cavity. The purpose of the present study was to investigate the status of salivary antioxidant and immunoglobulin E in patients with GT and healthy people. MATERIALS AND METHODS: In this case-control study, samples were gathered from high school students in three municipal regions of Kermanshah, Iran by using multistage random cluster sampling method. The samples included 30 patients with GT (15 men and 15 women with the mean age of 17.6 ± 0.72) and 30 healthy volunteers (15 men and 15 women with the mean age of 17.1 ± 0.61). Saliva samples were collected through standard method, and total antioxidant capacity (TAC), catalase (CAT), and salivary immunoglobulin E were measured. RESULTS: In patients with GT, unstimulated salivary shows increased level of immunoglobulin compared with that of control group (P = 0.013). However, there was no significant relationship between control and GT patient groups regarding TAC of saliva (P = 0.91) and CAT (P = 0.83). CONCLUSION: It seems that the activity of CAT enzyme and TAC of saliva does not play primary role in the pathogenesis of GT. However, the level of immunoglobulin E present in saliva can function as an indicator of increased sensitivity in GT. Wolters Kluwer - Medknow 2020-01-28 /pmc/articles/PMC7014838/ /pubmed/32110568 http://dx.doi.org/10.4103/jfmpc.jfmpc_375_19 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Rezaei, Fatemeh Fatholahi, Saeedeh Rezaei, Farzad Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue |
title | Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue |
title_full | Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue |
title_fullStr | Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue |
title_full_unstemmed | Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue |
title_short | Assessment of salivary antioxidant status and immunoglobulin E in patients with geographic tongue |
title_sort | assessment of salivary antioxidant status and immunoglobulin e in patients with geographic tongue |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014838/ https://www.ncbi.nlm.nih.gov/pubmed/32110568 http://dx.doi.org/10.4103/jfmpc.jfmpc_375_19 |
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