Cargando…

Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh

BACKGROUND: Dengue has emerged as a major public health problem in India. It presents more aggressively among younger age groups as compared to adults. Therefore, it necessitates the accurate estimation of prevalence in younger age groups. MATERIALS AND METHOD: Of all the 1026 clinically suspected c...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Manoj, Verma, Rajesh Kumar, Nirjhar, Suchitra, Singh, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014909/
https://www.ncbi.nlm.nih.gov/pubmed/32110607
http://dx.doi.org/10.4103/jfmpc.jfmpc_770_19
_version_ 1783496731845984256
author Kumar, Manoj
Verma, Rajesh Kumar
Nirjhar, Suchitra
Singh, Monika
author_facet Kumar, Manoj
Verma, Rajesh Kumar
Nirjhar, Suchitra
Singh, Monika
author_sort Kumar, Manoj
collection PubMed
description BACKGROUND: Dengue has emerged as a major public health problem in India. It presents more aggressively among younger age groups as compared to adults. Therefore, it necessitates the accurate estimation of prevalence in younger age groups. MATERIALS AND METHOD: Of all the 1026 clinically suspected cases of dengue up to the age of 18 years were enrolled in this study and grouped into four age groups (Group I - <0 to 1 year, Group II- 1 to 6 years, Group III- 7 to 12 years, and Group IV- 13 to 18 years). Their blood samples were aseptically collected from different clinical departments and were submitted to the Viral Research and Diagnostic Laboratory (VRDL), Department of Microbiology during the outbreak of 2016–17. Serum was separated and processed for dengue Non Structural Protein 1 antigen (NS1 Ag)and Immunoglobuline M antibody (IgM Ab) enzyme-linked immunosorbent assay (ELISA). All the relevant variables like age, sex, and demographic profile were recorded and statistically analyzed. RESULTS: A total 295 of the 1026 cases were detected positive for dengue either by NS1 Ag or IgM Ab ELISA. The results show the susceptibility to dengue being increased in the order of age Group I to IV. We analyzed the outbreak of year 2016 and 2017, of these 159/483 (33%) cases and 136/543 (25%) cases, respectively, were found seropositive during these years. The months of September, October, and November are more prone to dengue infection. CONCLUSION: Group III and IV were more susceptible to dengue fever (DF). The months of postmonsoon season are more favorable for spread of dengue among different age groups of the population.
format Online
Article
Text
id pubmed-7014909
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-70149092020-02-27 Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh Kumar, Manoj Verma, Rajesh Kumar Nirjhar, Suchitra Singh, Monika J Family Med Prim Care Original Article BACKGROUND: Dengue has emerged as a major public health problem in India. It presents more aggressively among younger age groups as compared to adults. Therefore, it necessitates the accurate estimation of prevalence in younger age groups. MATERIALS AND METHOD: Of all the 1026 clinically suspected cases of dengue up to the age of 18 years were enrolled in this study and grouped into four age groups (Group I - <0 to 1 year, Group II- 1 to 6 years, Group III- 7 to 12 years, and Group IV- 13 to 18 years). Their blood samples were aseptically collected from different clinical departments and were submitted to the Viral Research and Diagnostic Laboratory (VRDL), Department of Microbiology during the outbreak of 2016–17. Serum was separated and processed for dengue Non Structural Protein 1 antigen (NS1 Ag)and Immunoglobuline M antibody (IgM Ab) enzyme-linked immunosorbent assay (ELISA). All the relevant variables like age, sex, and demographic profile were recorded and statistically analyzed. RESULTS: A total 295 of the 1026 cases were detected positive for dengue either by NS1 Ag or IgM Ab ELISA. The results show the susceptibility to dengue being increased in the order of age Group I to IV. We analyzed the outbreak of year 2016 and 2017, of these 159/483 (33%) cases and 136/543 (25%) cases, respectively, were found seropositive during these years. The months of September, October, and November are more prone to dengue infection. CONCLUSION: Group III and IV were more susceptible to dengue fever (DF). The months of postmonsoon season are more favorable for spread of dengue among different age groups of the population. Wolters Kluwer - Medknow 2020-01-28 /pmc/articles/PMC7014909/ /pubmed/32110607 http://dx.doi.org/10.4103/jfmpc.jfmpc_770_19 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kumar, Manoj
Verma, Rajesh Kumar
Nirjhar, Suchitra
Singh, Monika
Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh
title Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh
title_full Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh
title_fullStr Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh
title_full_unstemmed Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh
title_short Dengue in children and young adults, a cross-sectional study from the western part of Uttar Pradesh
title_sort dengue in children and young adults, a cross-sectional study from the western part of uttar pradesh
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014909/
https://www.ncbi.nlm.nih.gov/pubmed/32110607
http://dx.doi.org/10.4103/jfmpc.jfmpc_770_19
work_keys_str_mv AT kumarmanoj dengueinchildrenandyoungadultsacrosssectionalstudyfromthewesternpartofuttarpradesh
AT vermarajeshkumar dengueinchildrenandyoungadultsacrosssectionalstudyfromthewesternpartofuttarpradesh
AT nirjharsuchitra dengueinchildrenandyoungadultsacrosssectionalstudyfromthewesternpartofuttarpradesh
AT singhmonika dengueinchildrenandyoungadultsacrosssectionalstudyfromthewesternpartofuttarpradesh