Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report

Anti-γ-aminobutyric acid B receptor (anti-GABA(B)R) encephalitis is a rare type of autoimmune encephalitis (AE). Although it responds well to immunomodulating therapy and has favorable prognosis, anti-GABA(B)R AE has often been misdiagnosed as infectious encephalitis. Herein, we present a case of a...

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Autores principales: Qin, Wei, Wang, Xiao, Yang, Jing, Hu, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015060/
https://www.ncbi.nlm.nih.gov/pubmed/32103919
http://dx.doi.org/10.2147/CIA.S234660
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author Qin, Wei
Wang, Xiao
Yang, Jing
Hu, Wenli
author_facet Qin, Wei
Wang, Xiao
Yang, Jing
Hu, Wenli
author_sort Qin, Wei
collection PubMed
description Anti-γ-aminobutyric acid B receptor (anti-GABA(B)R) encephalitis is a rare type of autoimmune encephalitis (AE). Although it responds well to immunomodulating therapy and has favorable prognosis, anti-GABA(B)R AE has often been misdiagnosed as infectious encephalitis. Herein, we present a case of a 59-year-old female with anti-GABA(B)R AE associated with small cell lung cancer (SCLC) that was once misdiagnosed as infectious encephalitis. Our findings increase the awareness that patients presenting with a clinical trial of cognitive impairment, seizures and SCLC may harbor AE. Our case also highlights the importance of anti-SOX1 antibody in the detection of SCLC.
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spelling pubmed-70150602020-02-26 Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report Qin, Wei Wang, Xiao Yang, Jing Hu, Wenli Clin Interv Aging Case Report Anti-γ-aminobutyric acid B receptor (anti-GABA(B)R) encephalitis is a rare type of autoimmune encephalitis (AE). Although it responds well to immunomodulating therapy and has favorable prognosis, anti-GABA(B)R AE has often been misdiagnosed as infectious encephalitis. Herein, we present a case of a 59-year-old female with anti-GABA(B)R AE associated with small cell lung cancer (SCLC) that was once misdiagnosed as infectious encephalitis. Our findings increase the awareness that patients presenting with a clinical trial of cognitive impairment, seizures and SCLC may harbor AE. Our case also highlights the importance of anti-SOX1 antibody in the detection of SCLC. Dove 2020-02-07 /pmc/articles/PMC7015060/ /pubmed/32103919 http://dx.doi.org/10.2147/CIA.S234660 Text en © 2020 Qin et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Qin, Wei
Wang, Xiao
Yang, Jing
Hu, Wenli
Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_full Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_fullStr Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_full_unstemmed Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_short Coexistence of Anti-SOX1 and Anti-GABA(B) Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_sort coexistence of anti-sox1 and anti-gaba(b) receptor antibodies with autoimmune encephalitis in small cell lung cancer: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015060/
https://www.ncbi.nlm.nih.gov/pubmed/32103919
http://dx.doi.org/10.2147/CIA.S234660
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