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Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon
The contribution of Anopheles funestus to malaria transmission in the urban environment is still not well documented. The present study assesses the implication of An. funestus in malaria transmission in two districts, Nsam and Mendong, in the city of Yaoundé. Adult mosquitoes were collected using C...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
EDP Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015064/ https://www.ncbi.nlm.nih.gov/pubmed/32048986 http://dx.doi.org/10.1051/parasite/2020005 |
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author | Djamouko-Djonkam, Landre Nkahe, Diane Leslie Kopya, Edmond Talipouo, Abdou Ngadjeu, Carmene Sandra Doumbe-Belisse, Patricia Bamou, Roland Awono-Ambene, Parfait Tchuinkam, Timoléon Wondji, Charles Sinclair Antonio-Nkondjio, Christophe |
author_facet | Djamouko-Djonkam, Landre Nkahe, Diane Leslie Kopya, Edmond Talipouo, Abdou Ngadjeu, Carmene Sandra Doumbe-Belisse, Patricia Bamou, Roland Awono-Ambene, Parfait Tchuinkam, Timoléon Wondji, Charles Sinclair Antonio-Nkondjio, Christophe |
author_sort | Djamouko-Djonkam, Landre |
collection | PubMed |
description | The contribution of Anopheles funestus to malaria transmission in the urban environment is still not well documented. The present study assesses the implication of An. funestus in malaria transmission in two districts, Nsam and Mendong, in the city of Yaoundé. Adult mosquitoes were collected using Centers for Disease Control and Prevention miniature light traps (CDC-LT) and human landing catches from April 2017 to March 2018 and were identified morphologically to the species level. Those belonging to the Anopheles gambiae complex and to the Anopheles funestus group were further processed by PCR to identify members of each complex/group. Anopheline mosquitoes were analysed to determine their infection status using an enzyme-linked immunosorbent assay. Bioassays were conducted with 2–5-day-old female Anopheles funestus and An. gambiae s.l. to determine their susceptibility to permethrin, deltamethrin and dichlorodiphenyltrichloroethane (DDT). Six anopheline species were collected in the peri-urban district of Mendong: Anopheles gambiae, An. coluzzii, An. funestus, An. leesoni, An. ziemanni and An. marshallii; only four out of the six were recorded in Nsam. Of the two members of the Anopheles gambiae complex collected, An. coluzzii was the most prevalent. Anopheles coluzzii was the most abundant species in Nsam, while An. funestus was the most abundant in Mendong. Both Anopheles funestus and An. gambiae s.l. were found to be infected with human Plasmodium at both sites, and both were found to be resistant to DDT, permethrin, and deltamethrin. This study confirms the participation of An. funestus in malaria transmission in Yaoundé and highlights the need to also target this species for sustainable control of malaria transmission. |
format | Online Article Text |
id | pubmed-7015064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | EDP Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-70150642020-02-27 Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon Djamouko-Djonkam, Landre Nkahe, Diane Leslie Kopya, Edmond Talipouo, Abdou Ngadjeu, Carmene Sandra Doumbe-Belisse, Patricia Bamou, Roland Awono-Ambene, Parfait Tchuinkam, Timoléon Wondji, Charles Sinclair Antonio-Nkondjio, Christophe Parasite Research Article The contribution of Anopheles funestus to malaria transmission in the urban environment is still not well documented. The present study assesses the implication of An. funestus in malaria transmission in two districts, Nsam and Mendong, in the city of Yaoundé. Adult mosquitoes were collected using Centers for Disease Control and Prevention miniature light traps (CDC-LT) and human landing catches from April 2017 to March 2018 and were identified morphologically to the species level. Those belonging to the Anopheles gambiae complex and to the Anopheles funestus group were further processed by PCR to identify members of each complex/group. Anopheline mosquitoes were analysed to determine their infection status using an enzyme-linked immunosorbent assay. Bioassays were conducted with 2–5-day-old female Anopheles funestus and An. gambiae s.l. to determine their susceptibility to permethrin, deltamethrin and dichlorodiphenyltrichloroethane (DDT). Six anopheline species were collected in the peri-urban district of Mendong: Anopheles gambiae, An. coluzzii, An. funestus, An. leesoni, An. ziemanni and An. marshallii; only four out of the six were recorded in Nsam. Of the two members of the Anopheles gambiae complex collected, An. coluzzii was the most prevalent. Anopheles coluzzii was the most abundant species in Nsam, while An. funestus was the most abundant in Mendong. Both Anopheles funestus and An. gambiae s.l. were found to be infected with human Plasmodium at both sites, and both were found to be resistant to DDT, permethrin, and deltamethrin. This study confirms the participation of An. funestus in malaria transmission in Yaoundé and highlights the need to also target this species for sustainable control of malaria transmission. EDP Sciences 2020-02-12 /pmc/articles/PMC7015064/ /pubmed/32048986 http://dx.doi.org/10.1051/parasite/2020005 Text en © L. Djamouko-Djonkam et al., published by EDP Sciences, 2020 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Djamouko-Djonkam, Landre Nkahe, Diane Leslie Kopya, Edmond Talipouo, Abdou Ngadjeu, Carmene Sandra Doumbe-Belisse, Patricia Bamou, Roland Awono-Ambene, Parfait Tchuinkam, Timoléon Wondji, Charles Sinclair Antonio-Nkondjio, Christophe Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon |
title | Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon |
title_full | Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon |
title_fullStr | Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon |
title_full_unstemmed | Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon |
title_short | Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon |
title_sort | implication of anopheles funestus in malaria transmission in the city of yaoundé, cameroon |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015064/ https://www.ncbi.nlm.nih.gov/pubmed/32048986 http://dx.doi.org/10.1051/parasite/2020005 |
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