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Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon

The contribution of Anopheles funestus to malaria transmission in the urban environment is still not well documented. The present study assesses the implication of An. funestus in malaria transmission in two districts, Nsam and Mendong, in the city of Yaoundé. Adult mosquitoes were collected using C...

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Autores principales: Djamouko-Djonkam, Landre, Nkahe, Diane Leslie, Kopya, Edmond, Talipouo, Abdou, Ngadjeu, Carmene Sandra, Doumbe-Belisse, Patricia, Bamou, Roland, Awono-Ambene, Parfait, Tchuinkam, Timoléon, Wondji, Charles Sinclair, Antonio-Nkondjio, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015064/
https://www.ncbi.nlm.nih.gov/pubmed/32048986
http://dx.doi.org/10.1051/parasite/2020005
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author Djamouko-Djonkam, Landre
Nkahe, Diane Leslie
Kopya, Edmond
Talipouo, Abdou
Ngadjeu, Carmene Sandra
Doumbe-Belisse, Patricia
Bamou, Roland
Awono-Ambene, Parfait
Tchuinkam, Timoléon
Wondji, Charles Sinclair
Antonio-Nkondjio, Christophe
author_facet Djamouko-Djonkam, Landre
Nkahe, Diane Leslie
Kopya, Edmond
Talipouo, Abdou
Ngadjeu, Carmene Sandra
Doumbe-Belisse, Patricia
Bamou, Roland
Awono-Ambene, Parfait
Tchuinkam, Timoléon
Wondji, Charles Sinclair
Antonio-Nkondjio, Christophe
author_sort Djamouko-Djonkam, Landre
collection PubMed
description The contribution of Anopheles funestus to malaria transmission in the urban environment is still not well documented. The present study assesses the implication of An. funestus in malaria transmission in two districts, Nsam and Mendong, in the city of Yaoundé. Adult mosquitoes were collected using Centers for Disease Control and Prevention miniature light traps (CDC-LT) and human landing catches from April 2017 to March 2018 and were identified morphologically to the species level. Those belonging to the Anopheles gambiae complex and to the Anopheles funestus group were further processed by PCR to identify members of each complex/group. Anopheline mosquitoes were analysed to determine their infection status using an enzyme-linked immunosorbent assay. Bioassays were conducted with 2–5-day-old female Anopheles funestus and An. gambiae s.l. to determine their susceptibility to permethrin, deltamethrin and dichlorodiphenyltrichloroethane (DDT). Six anopheline species were collected in the peri-urban district of Mendong: Anopheles gambiae, An. coluzzii, An. funestus, An. leesoni, An. ziemanni and An. marshallii; only four out of the six were recorded in Nsam. Of the two members of the Anopheles gambiae complex collected, An. coluzzii was the most prevalent. Anopheles coluzzii was the most abundant species in Nsam, while An. funestus was the most abundant in Mendong. Both Anopheles funestus and An. gambiae s.l. were found to be infected with human Plasmodium at both sites, and both were found to be resistant to DDT, permethrin, and deltamethrin. This study confirms the participation of An. funestus in malaria transmission in Yaoundé and highlights the need to also target this species for sustainable control of malaria transmission.
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spelling pubmed-70150642020-02-27 Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon Djamouko-Djonkam, Landre Nkahe, Diane Leslie Kopya, Edmond Talipouo, Abdou Ngadjeu, Carmene Sandra Doumbe-Belisse, Patricia Bamou, Roland Awono-Ambene, Parfait Tchuinkam, Timoléon Wondji, Charles Sinclair Antonio-Nkondjio, Christophe Parasite Research Article The contribution of Anopheles funestus to malaria transmission in the urban environment is still not well documented. The present study assesses the implication of An. funestus in malaria transmission in two districts, Nsam and Mendong, in the city of Yaoundé. Adult mosquitoes were collected using Centers for Disease Control and Prevention miniature light traps (CDC-LT) and human landing catches from April 2017 to March 2018 and were identified morphologically to the species level. Those belonging to the Anopheles gambiae complex and to the Anopheles funestus group were further processed by PCR to identify members of each complex/group. Anopheline mosquitoes were analysed to determine their infection status using an enzyme-linked immunosorbent assay. Bioassays were conducted with 2–5-day-old female Anopheles funestus and An. gambiae s.l. to determine their susceptibility to permethrin, deltamethrin and dichlorodiphenyltrichloroethane (DDT). Six anopheline species were collected in the peri-urban district of Mendong: Anopheles gambiae, An. coluzzii, An. funestus, An. leesoni, An. ziemanni and An. marshallii; only four out of the six were recorded in Nsam. Of the two members of the Anopheles gambiae complex collected, An. coluzzii was the most prevalent. Anopheles coluzzii was the most abundant species in Nsam, while An. funestus was the most abundant in Mendong. Both Anopheles funestus and An. gambiae s.l. were found to be infected with human Plasmodium at both sites, and both were found to be resistant to DDT, permethrin, and deltamethrin. This study confirms the participation of An. funestus in malaria transmission in Yaoundé and highlights the need to also target this species for sustainable control of malaria transmission. EDP Sciences 2020-02-12 /pmc/articles/PMC7015064/ /pubmed/32048986 http://dx.doi.org/10.1051/parasite/2020005 Text en © L. Djamouko-Djonkam et al., published by EDP Sciences, 2020 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Djamouko-Djonkam, Landre
Nkahe, Diane Leslie
Kopya, Edmond
Talipouo, Abdou
Ngadjeu, Carmene Sandra
Doumbe-Belisse, Patricia
Bamou, Roland
Awono-Ambene, Parfait
Tchuinkam, Timoléon
Wondji, Charles Sinclair
Antonio-Nkondjio, Christophe
Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon
title Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon
title_full Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon
title_fullStr Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon
title_full_unstemmed Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon
title_short Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon
title_sort implication of anopheles funestus in malaria transmission in the city of yaoundé, cameroon
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015064/
https://www.ncbi.nlm.nih.gov/pubmed/32048986
http://dx.doi.org/10.1051/parasite/2020005
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