Cargando…
Metformin attenuates the D-galactose-induced aging process via the UPR through the AMPK/ERK1/2 signaling pathways
Age-related hearing loss, also termed central presbycusis, is a progressive neurodegenerative disease; it is a devastating disorder that severely affects the quality of life of elderly individuals. Substantial evidence has indicated that oxidative stress and associated protein folding dysfunction ha...
Autores principales: | Cai, Hua, Han, Baoai, Hu, Yujuan, Zhao, Xueyan, He, Zuhong, Chen, Xubo, Sun, Haiying, Yuan, Jie, Li, Yongqin, Yang, Xiuping, Kong, Wen, Kong, Wei-Jia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015132/ https://www.ncbi.nlm.nih.gov/pubmed/31922237 http://dx.doi.org/10.3892/ijmm.2020.4453 |
Ejemplares similares
-
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways
por: Chen, Xubo, et al.
Publicado: (2017) -
Age-associated decline in Nrf2 signaling and associated mtDNA damage may be involved in the degeneration of the auditory cortex: Implications for central presbycusis
por: Li, Yongqin, et al.
Publicado: (2018) -
Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts
por: Leclerc, Gilles M., et al.
Publicado: (2013) -
Correlation between mitochondrial DNA 4977 bp deletion and presbycusis: A system review and meta-analysis
por: Han, Baoai, et al.
Publicado: (2019) -
Hydrogen Sulphide Treatment Increases Insulin Sensitivity and Improves Oxidant Metabolism through the CaMKKbeta-AMPK Pathway in PA-Induced IR C2C12 Cells
por: Chen, Xubo, et al.
Publicado: (2017)