Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

Follicular dendritic cells (FDCs), a rare and enigmatic stromal cell type in the B cell follicles of secondary lymphoid organs, store and present antigen to B cells. While essential for germinal center (GC) responses, their exact role during GC B cell selection remains unknown. FDCs upregulate the i...

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Detalles Bibliográficos
Autores principales: van der Poel, Cees E., Bajic, Goran, Macaulay, Charles W., van den Broek, Theo, Ellson, Christian D., Bouma, Gerben, Victora, Gabriel D., Degn, Søren E., Carroll, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015177/
https://www.ncbi.nlm.nih.gov/pubmed/31775042
http://dx.doi.org/10.1016/j.celrep.2019.10.086

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